The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
Oral Immunotherapy for Peanut Allergies Improves Quality of Life Post-Treatment
A meta-analysis found oral immunotherapy improves health-related quality of life post-food allergy treatment, but benefits during treatment remain unclear.
Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis
In new data to be presented at AAAAI, the therapy was well-tolerated in people as young as 2 years old.
Add-on Remibrutinib Quickly Improves Urticaria Control in CSU
By week 52, remibrutinib and placebo-to-remibrutinib groups had similar levels of urticaria control.
Ruxolitinib Shows Clinical Benefit in Children, Adults With Atopic Dermatitis
Data from 3 pooled phase 3 studies in children, adolescents, and adults will be presented at the AAAI/WAO Joint Congress.
Unmet Need for Advanced Chronic Spontaneous Urticaria Treatments Highlighted in Study
A study found many patients with chronic spontaneous urticaria need add-on or higher-dose therapies, revealing gaps in treatment. Findings will be presented at AAAAI 2025.
Rilzabrutinib Yields Responses in Angioedema in People With CS Urticaria
At week 12, a higher proportion of participants on rilzabrutinib 1200mg a day (60.9%) achieved AAS7 scores of 0 than placebo-treated participants (30.8%).
Skin Barrier Dysfunction in Infants’ Cheeks May Predict Atopic Dermatitis Development
Infants who develop atopic dermatitis show early cheek skin barrier dysfunction with delayed FLG processing, low ceramides, and high IL-18. The study will be presented at AAAAI 2025.
Navenibart Reduces Hereditary Angioedema Burden in Small Study’s Interim Analysis
At 6 months, baseline monthly rates of 0.45 for mild, 1.54 for moderate, and 0.14 for severe attacks were reduced to 0.10, 0.08, and 0.00, respectively.
Understanding Angioedema in Urticaria, with Jonathan Bernstein, MD
Bernstein discussed recent and upcoming research and management of angioedema in patients with urticaria.
Dupilumab May Improve Growth in Children with Severe Atopic Dermatitis by 16 Weeks
Children with severe atopic dermatitis saw > 5 percentile height gains after 16 weeks of dupilumab, per a study to be presented at AAAAI 2025.
Solar Urticaria More Prevalent in Women, UV and Visible Light Both Common Triggers
Around half of participants had insufficient vitamin D levels.
Skin Barrier Meter Safely Measures Stratum Corneum Changes in Atopic Dermatitis
A study found the Skin Barrier Meter accurately measures skin barrier function in children with atopic dermatitis, offering a fast, non-invasive assessment within 5 seconds.
Contact Dermatitis to Common Wound Care Products Exacerbates Chronic Ulcers
Fifteen of 16 patients with chronic ulcers in a small study had positive patch test to common wound care products.
16 CpG Sites in DNA at Birth Linked to Early-Onset Atopic Dermatitis
A study found distinct DNA methylation patterns at birth linked to early-onset atopic dermatitis by age 2. Findings will be presented at AAAAI 2025.
Bimekizumab Long-Term Hidradenitis Suppurativa Data Support Efficacy, Safety Profile
New 2-year data from the BE HEARD program shed further light on the role bimekizumab in treatment algorithms for HS.
Avapritinib Improves Outcomes in Indolent Systemic Mastocytosis in Real-World Data
Avapritinib 25mg daily significantly improved quality of life (QoL), disease control, and basal serum tryptase (BST) levels.
Dupilumab Reduces Itch, Urticaria Activity in Chronic Spontaneous Urticaria
A pooled analysis of LIBERTY-CSU CUPID Study A and Study C showed dupilumab reduces itch in patients with chronic spontaneous urticaria by week 24.
Caroline Piatek, MD: High HCRU, Patient Concerns Highlight Great Unmet Need in wAIHA
Piatek discussed findings from a healthcare resource utilization study and a sentiment analysis study presented at ASH 2024.
Steven W. Pipe, MD: Supporting Gene Therapy Implementation for Hemophilia
Pipe discussed a symposium at ASH 2024 about practical implementation of gene therapy in the field.
Corinna L. Schultz, MD: Improving Sickle Cell Trait Documentation in Infancy
Schultz discussed the SCtalk trial and its findings at ASH 2024.
Sibgha Zaheer, MD: Determining Washout Period With Fitusiran, Emicizumab Transition for Hemophilia
Zaheer discussed how this research may be used as a model to help study other therapy transitions as well.
Pavan K. (Tem) Bendapudi, MD: Large-Scale Analyses Elucidate Genetic Risk of Thrombosis
Bendapudi gave an overview of 2 studies presented at ASH 2024 from his Harvard lab.
Seema Rani, MD: Examining Sleep Health in Youth With SCD
Rani discussed an in-depth study examining quality of sleep and quality of life in children and adolescents with SCD.
Daniel Wang: A More Appropriate Ferritin Threshold is Cost-Effective for Iron Deficiency Screening
Iron deficiency is currently screened at a ferritin threshold of 15 ug/mL, well below an accepted 25 ug/mL threshold.
Kimberly A. Davidow, MD: Elucidating Risk of Autoimmune Disease in Childhood Cancer Survivors
Davidow discussed how a new cohort study has helped support findings of an older European study and the need for a prospective trial to confirm the increased risk.
Yehuda Handelsman, MD: Key Highlights, Takeaways from WCIRDC 2024
Yehuda Handelsman, MD reflects on the WCIRDC 2024’s comprehensive approach to advancing cardiometabolic care through multidisciplinary collaboration.
Yehuda Handelsman, MD: Insulin Resistance in Cardiometabolic Disease and DCRM 2.0
Yehuda Handelsman, MD highlights insulin resistance’s role in cardiometabolic disease and introduces DCRM 2.0 as a global, multi-specialty care framework.
Julia Weisinger, MD: Obinutuzumab a Promising Option for Intolerant/Refractory iTTP
Weisinger discussed findings from the largest cohort of patients with iTTP treated with Obinutuzumab.
Nathan D. Wong, MPH, PhD: Growing Role of Lp(a) in Cardiovascular Risk Assessment
Nathan D. Wong, MPH, PhD discusses the evolution of Lp(a) in risk assessment, given its role as a genetic risk factor for cardiovascular complications.
Laurence Sperling, MD: Expanding Cardiologists' Role in Obesity Management
Laurence Sperling, MD described the evolving role of cardiologists in obesity care, particularly with the increasing adoption of therapies such as GLP-1 agonists.