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New PKU Drug Already Benefiting AdultsThe recently approved phenylketonuria (PKU) drug, pegvaliase, is helping patients experience less disease burden—and drastically in some cases.
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The Effect of AL AmyloidosisHeather Landau, M.D., Assistant Attending Physician at the Memorial Sloan Kettering Cancer Center, explains AL Amyloidosis. In this video, she describes in detail the clinical definition of the disease, what organs are affected, and early presentation.
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C-reactive protein and hypertensionWe assessed whether C-reactive protein (CRP) concentrations predicted future risk of hypertension in a cohort of young adults. Results showed that CRP levels do not independently predict risk of incident hypertension after accounting for body mass index. Further research is needed in the area of inflammation and hypertension, with a special focus on the effect of obesity and age-related changes on this process.
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Surgical Treatment of Moderate Ischemic Mitral RegurgitationThe addition of a mitral valve repair to patients undergoing coronary artery bypass graft (CABG) surgery with moderate ischemic mitral regurgitation is still a source of controversy. Recent guidelines state that concomitant mitral valve repair at the time of CABG may be beneficial, but the evidence is inconclusive.
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What I Learned at the AAPL Conference: Part 3Continued coverage of the American Academy of Psychiatry and Law (AAPL) conference.
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Using Ultrasound to Accurately Diagnose Pediatric Skull FracturesUltrasound can lessen the need for head scans in children and reduce the impact of radiation on the developing brains of those who are particularly sensitive to ionizing radiation.
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Getting the Most Out of Your iPhoneCheck out these suggestions on how to maximize battery life and up-time and other tips and tricks to help you get maximum performance from your iPhone.
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UK Study: Nearly Half Asthma Deaths PreventableNearly half of asthma deaths in the United Kingdom could likely have been prevented, researchers there found.
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The Face of Pain: Treating Trigeminal NeuralgiaTrigeminal neuralgia, or tic doloureux, is one of the least recognized and most excruciating chronic pain conditions. Anticonvulsants have been shown to be effective, but some patients require surgical intervention to find relief from the pain.
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Atorvastatin pretreatment in early percutaneous coronary interventionAccording to results of the Atorvastatin for Reduction of Myocardial Damage During Angioplasty-Acute Coronary Syndromes (ARMYDA-ACS) trial, short-term pretreatment with high-dose atorvastatin prior to percutaneous coronary intervention improves clinical outcome in subjects with unstable angina and non-ST-segment elevation myocardial infarction. These findings support the upstream administration of high-dose statins in subjects with acute coronary syndrome treated with an early invasive strategy.
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Alogliptin: The newest agent to fight the diabetes pandemicAccording to the American Diabetes Association (ADA), 23.6 million children and adults have diabetes (8% of the US population) and another 5.7 million cases remain undiagnosed. Epidemiologists predict that these statistics will double by 2030, further taxing the healthcare system. Medical expenditures are approximately 2.3 times higher for diabetic versus nondiabetic patients, and the annual cost of diabetes is estimated to be $116 billion.
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Beth Israel Deaconess Medical Center Releases iPhone App for PatientsThe app is "aimed squarely at patients," according to iMedical Apps editors, enabling them to learn about the medical center and affiliated doctors.
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Has the RUC Destroyed Medical Student Interest in Primary Care?Are the policies and actions of the AMA's Specialty Society Relative Value Scale Update Committee (RUC) to blame for the looming primary care shortage?
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Antithrombotic treatment of high-risk elderly patients hospitalized with atrial fibrillationWe assessed the pattern of use and the effectiveness of antithrombotic therapy in a cohort of high-risk elderly patients hospitalized for atrial fibrillation, with data derived from prescription, hospitalization, and mortality databases from 3 linked registries. Results showed that antithrombotic therapy was underused, even in patients with no comorbid conditions. In addition, patients exposed to antithrombotic therapy had a significantly lower mortality rate. The collection of epidemiological data by record linkage represents a flexible and readily available tool for monitoring and improving routine clinical care.
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Impact of diabetes development on atrial fibrillation in hypertensive patientsPatients with new-onset diabetes mellitus in the VALUE (Valsartan Antihypertensive Long-term Use Evaluation) trial had an increased incidence of atrial fibrillation compared with patients without diabetes. Clustering of risk factors or the presence of dysglycemia may make the heart more susceptible to arrhythmias.
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Clostridium Difficile Infection Associated With Higher Mortality Rates in Patients With CirrhosisClostridium difficile infection leads to higher rates of overall mortality among patients with cirrhosis compared to those who do not have the condition.
