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Reducing inflammatory biomarkers: What does it mean?The principal finding of this study is that among patients with type II diabetes and mixed dyslipidemia, treatment with simvastatin, fenofibrate, or their combination was associated with reductions in inflammatory biomarkers high-sensitivity C-reactive protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2).
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Older Nurses in the WorkforceA topic that is being discussed a lot these days is older nurses in the workforce. The American Nurses Association reports that the average age of an RN is now 45.2 years, with nurses younger than 30 years making up only 8% of the workforce.
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Decision Support Systems in Oncology: Are we there yet?The push for clinical decision support technology in medicine is a logical consequence of our experiences as consumers and the need for intelligent support at the bedside.
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Mobile Users are Moving Targets in a Dangerous Online WorldAlthough more people than ever use their smartphones to access the Internet, few take the time to think about issues of mobile Internet safety.
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Human Papillomavirus Infection: Current Approach to PreventionPreventing HPV infection is tantamount to cervical cancer eradication. New vaccines offer protection against many HPV serotypes, but even vaccinated women should be screened for cervical cancer.
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White-coat hypertension and progression to home hypertensionOur study aimed to clarify whether white-coat hypertension represents a transient state in the development of hypertension outside medical settings. We followed up 128 subjects with white-coat hypertension and compared their risk of progression to home hypertension with that of 649 sustained normotensive subjects. After 8 years of follow-up, subjects with white-coat hypertension had an approximately 3-fold higher risk of eventually manifesting home hypertension. We concluded that patients with white-coat hypertension should be carefully monitored.
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Web-based Activities to Promote Behavior ChangeThe Internet can be a powerful tool for promoting health with its abundant resources on adopting and maintaining a healthy lifestyle.
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C-reactive protein and hypertensionWe assessed whether C-reactive protein (CRP) concentrations predicted future risk of hypertension in a cohort of young adults. Results showed that CRP levels do not independently predict risk of incident hypertension after accounting for body mass index. Further research is needed in the area of inflammation and hypertension, with a special focus on the effect of obesity and age-related changes on this process.
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The Birth of a New Decade: Will We Finally Improve Maternal Care in the US?Providers must look at their maternal health models to ensure patients are receiving the best care.
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Dealing with Treatment Adherence Issues in Acute ConditionsToo often, patients seek help and receive medical advice but return for follow-up with less-than-optimal improvement because they did not comply with recommended therapy. Costs of nonadherence add to the economic burden of health care in the United States and interfere with appropriate treatment. By discussing with the patient anticipated barriers, such as perceived side effects or regimen complexity, the physician can significantly improve outcomes. The authors outline ways to enhance patient compliance and improve the clinical picture while reducing costs.
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Targeted Interventions : Reengagement in Care of People Living with HIVKeeping some patients with HIV in care can be a challenge.
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How to Find Money Under Your Own RoofIf someone told you there are thousands of dollars hidden somewhere in your building, would you look for it? Medical practices are prime candidates for a cost segregation study, which can save thousands in taxes.
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Study Finds Wide Variation in the Use of Testosterone Therapy among Veterans Health Administration FacilitiesResearchers identify limited evidence base and uneven clinical application as probable reasons for variation.
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Recent Trends in Medical Simulation, with Implications for Open-Source SoftwareMedical simulation applies a numerical algorithm that synthesizes a clinical effect on a digital representation of patient anatomy.
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Early statin therapy in acute coronary syndromePatients who survive an acute coronary syndrome are at much higher risk of a recurrent event within the following month than patients with stable coronary syndromes. Statin therapy lowers the risk of recurrent events for many years but also reduces the risk of another event within the weeks to months following the initial acute coronary syndrome. The mechanisms that contribute to this benefit are likely related to improved endothelial function, decreased vascular inflammation, and reduced prothrombotic factors. Observation studies show an early reduction in mortality with statin therapy started before discharge from the hospital after an acute coronary syndrome.
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Does Anger Predict a Higher Likelihood of Cardiovascular Events?This meta-analysis attempts to definitively answer questions about the role of anger in cardiovascular events.
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Treatment Strategies in Hepatitis CThe most important treatment outcome in hepatitis C is sustained virological response, due to its impact on reducing the risks of liver-related mortality, hepatocellular carcinoma, and hepatic decompensation. The degree of baseline liver disease, IL28B genotype, and HCV genotype are important determinants of response to treatment.
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Is circulating heat shock protein 60 a marker for susceptibility to cardiovascular disease in patients with diabetes?The vital cell stress protein, heat shock protein (Hsp)60, has recently been found in the circulation of healthy subjects over an extremely large concentration range. We performed an analysis of subjects with diabetes to determine whether Hsp60 is associated with biochemical markers of cardiovascular disease. Results showed that high circulating levels of Hsp60 are associated with clinically manifest cardiovascular disease. Hsp60 has cytokine-like actions, which may be responsible for this association.
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Early Initiation of Rivipansel for VOC in Sickle Cell DiseaseEarly initiation reduces hospital stays and length of IV opioid use.
