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Prediction of coronary artery disease in patients with diabetes and albuminuriaWe developed a set of equations to predict the risk or probability of developing coronary artery disease (CAD) in 10 years among American Indians. The equations are based on the significant risk factors identified in the Strong Heart Study, a longitudinal study of cardiovascular disease in American Indians. The equations can be used in patient education and to evaluate the efficacy of CAD prevention and intervention programs.
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Effectiveness and Cost-Effectiveness of Diabetes Prevention among Adherent ParticipantsOver 10 years, lifestyle intervention and metformin were cost-effective or cost saving compared with placebo.
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Advances in Preventing and Diagnosing Cervical CancerAdvances in screening and the approval of vaccines against the human papillomavirus (HPV), which causes 70% of cervical cancer cases, have brought us to a turning point with cervical cancer.
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Dermatology Care Limited in Rural American Indian CommunitiesBoth brick-and-mortar dermatology clinics as well as telehealth programs are limited and restricted by barriers to access.
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Untreated diabetes mellitus in coronary artery by pass graft surgeryLauruschkat and colleagues entitled their article "Undiagnosed diabetes mellitus in coronary artery bypass graft surgery."
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New-Onset Diabetes and Ketoacidosis in a Patient Treated with OlanzapineSeveral case reports published since the introduction of atypical antipsychotics suggest an association between these medications and both new-onset diabetes mellitus and diabetic ketoacidosis. The latter is a potentially life threatening medical emergency. We report the case of a 41-year-old African American woman with schizophrenia who developed type 2 diabetes and ketoacidosis 7 months after commencing olanzapine therapy. This case adds to the evidence in the literature that patients who develop ketoacidosis while taking antipsychotic medications tend to be female and relatively young, a disproportionate number of whom are African American. The frequency of these reports suggests that clinicians should monitor serum glucose levels periodically in all patients treated with atypical antipsychotics, particularly in those at increased risk for diabetes.
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Life in the Balance: Perspectives on Stem Cell ResearchDavid Gollaher, president and CEO of California Healthcare Institute, discusses the tensions between stem cell research, ethics, and politics.
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Analysis of regional left ventricular functionWe performed cineventriculography, unenhanced echocardiography, contrast-enhanced echocardiography, and magnetic resonance imaging to define the presence of regional left ventricular wall motion abnormalities. Interobserver agreement in the analysis of regional wall motion abnormality was highest for contrast-enhanced echocardiography, followed by cineventriculography and cardiac magnetic resonance imaging; it was lowest for unenhanced echocardiography. Contrast-enhanced echocardiography also showed the highest accuracy in the detection of panel-defined regional wall motion abnormalities.
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Effect of medication nonadherence in diabetes mellitusWe evaluated the association between medication nonadherence and outcomes among subjects with diabetes mellitus. Nonadherent subjects had higher blood pressure, glycosylated hemoglobin, and low-density lipoprotein cholesterol levels. In addition, there was an association between medication nonadherence and an increased risk of all-cause hospitalization and all-cause mortality. These findings suggest that interventions are needed to increase medication adherence so that patients can realize the full benefit of prescribed therapies.
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We're Not Providers for Consumers/ClientsWhat has happened to make receiving health care like buying a car?
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Protecting from Alzheimer in the Female BrainThe fact that nearly 7 of every 10 Alzheimer diagnoses are made in women is not just associated with longer age expectancy.
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Smoking Associated with Negative COPD Exacerbator RelationshipResearchers determined that no relationship existed between haptoglobin polymorphism and frequent exacerbator status, though a negative one existed between exacerbator status and current smoking habits.
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White-coat hypertension and progression to home hypertensionOur study aimed to clarify whether white-coat hypertension represents a transient state in the development of hypertension outside medical settings. We followed up 128 subjects with white-coat hypertension and compared their risk of progression to home hypertension with that of 649 sustained normotensive subjects. After 8 years of follow-up, subjects with white-coat hypertension had an approximately 3-fold higher risk of eventually manifesting home hypertension. We concluded that patients with white-coat hypertension should be carefully monitored.
