Endocrinology

Principal investigator of the SURPASS-2 trial discusses the results of the trial and how it informs clinicians on the use of tirzepatide versus currently approved diabetes medications.

Three separate doses of the drug showed benefit when compared to semaglutide.

A major analysis suggests 2 servings of fruit and 3 servings of vegetables daily was linked to the greatest overall longevity and a 12% reduction in risk of death from cardiovascular disease.

After providing insight into the results of the STEP 1 and STEP 3 trials, Dr. Wadden discusses who he believes the responsibility for prescribing these medications will fall unto if semaglutide receives approval as a weight loss agent.

Patients ≥65 years using glargine or detemir, rather than NPH insulin, had lower risk of hospitalizations or emergency department visits due to hypoglycemia.

An analysis of data from 2 major studies suggests women with childhood-onset type 1 diabetes experienced 2.5 fewer reproductive years than their counterparts without diabetes.

An analysis of data from the Veterans Health Administration is providing insight into the apparent increase in risk of fracture or osteoporosis among older adults with kidney or ureteral stones.

Published in late February, results of the STEP 1 and STEP 3 trial give clinicians insight into the effects of 2.4 mg subcutaneous semaglutide as an intervention for weight loss in overweight or obese patients ahead of a potential approval in June 2021.

Results of a two-sample Mendelian randomization analysis suggest vitamin D levels were unlikely to have a large effect on a person's risk for developing type 1 diabetes.

An AHA study suggests nearly 66% of all COVID-19 hospitalizations could be attributed to the presence of obesity, diabetes, hypertension, or heart failure.

An analysis of more than 30k middle-aged adults from a prospective cohort study in Sweden is providing insight into the effects of exercise and other variables on fracture risk in these patients.

An analysis of nearly 500 patients hospitalized with COVID-19 from London suggests dysnatremia could help signal which patients were at an increased risk of complications, including death and need for respiratory support.

The authors of a research letter say a small minority of patients with diabetes have facial pain that cannot otherwise be easily explained.

A study of 80 young women is providing clinicians with insight into how total body fat can impact the timing of puberty and levels of pubertal hormones in women.

A review of 39 randomized clinical trials examining weight loss interventions is providing clinicians with an overview of engagement rates, mediums used, and effects of digital self-monitoring for weight loss among obese or overweight patients.

The reason for this decline has yet to be ascertained and thus warrants future research.

An analysis of data from more than 130 women suggests hypertensive disorders of pregnancy were associated with cardiac remodeling and risk of cardiovascular disease later in life.

Our latest case report from Dr. Brady Pregerson features a woman in her 50s presenting with cough, tactile fever, and shortness of breath. Can you determine the correct diagnosis?

Helen R. Murphy, MD, explains that physicians who take a proactive approach to diabetes management in women planning to become pregnant can make meaningful reductions in risk.

Data from a 20-year follow-up of gender diverse individuals indicate transgender men receiving testosterone therapy were at an 11% increased risk of developing erythrocytosis.

An analysis of more than 2k mother-child pairs indicates assessments of maternal cardiovascular health could shed light on the potential for poor cardiovascular health among their children at ages 10-14 years.

Our latest case report from Brady Pregerson, MD, features a 62 y/o male with a history of obesity, CAD, anxiety, and COPD presenting with SOB after stating cefalexin. Can you determine the correct diagnosis?

This episode of the Endocrine Outlook podcast features an interview on dietary interventions and the role of nutrition in obesity management with Ariana Chao, PhD, CRNP, of the University of Pennsylvania.

A survey of providers within the IOF and NOF provides insight into the effects of the COVID-19 pandemic on the diagnosis and treatment of osteoporosis across multiple regions throughout the world.

An analysis of data from the UK Biobank cohort is adding to the understanding of HbA1c and neurological health, suggesting patients with prediabetes were at an increased risk of cognitive decline and vascular dementia.

An analysis of data from the TRUST trial supports guideline recommendations against levothyroxine for reducing depressive symptoms in older adults with subclinical hypothyroidism.

The new study underscores the importance of annual urine analysis to catch signs of diabetic nephropathy.

An analysis of data from an ethnically diverse cohort of more than 120k patients indicates Chinese adults were more susceptible to obesity-related health complications, such as hypertension, than other racial/ethnic groups.

An analysis of more than 200 children indicates type 1 diabetes was linked to persistent differences in total IQ and white matter volume among children with type 1 diabetes.

Tubeless subcutaneous insulin injection devices are easier to use, but new data suggest they can also improve A1C outcomes.