Psoriatic Arthritis

A new patient registry analysis assessed whether there were any significant differences in outcome between combination therapy and monotherapy in patients with psoriatic arthritis.

Investigators looking to compare the risks of 13 different targeted immunomodulators gathered 51 observational studies and 10 randomized controlled trials that made head-to-head comparisons. Most of the studies involved patients with rheumatoid arthritis but the underlying research also included patients with ankylosing spondylitis, inflammatory bowel diseases, juvenile idiopathic arthritis, plaque psoriasis, psoriatic arthritis

Graded drug challenges are considered the gold standard for evaluating patients with a low-risk history of a prior adverse drug reactions – like a mild rash or unknown reaction to penicillin as a child.

High levels of soluble biglycan (sBGN) are present in the synovial fluid of patients with severe osteoarthritis and rheumatoid arthritis. While the connection between sBGN and inflammation had been established by previous research, this study is among the first to demonstrate that higher concentrations of sBGN are present in more severe arthritis cases.

A literature review concluded that multi-faceted interventions can lead patients with psoriatic arthritis and other immune-mediated inflammatory disorders to improve their adherence to treatment regimens.

The European League Against Rheumatism (EULAR) has drawn upon 3 years of fresh research to update its guidelines for the systematic management of psoriatic arthritis for the first time since 2012.

New research on the cost of treating psoriatic arthritis indicates that, on average, the annual bill for medical care and prescription medication totals just under $20,000 per patient, but that total costs vary greatly among individual patients.

The development pipeline for psoriasis in summary.

Price increases for psoriasis have consistently outpaced the Consumer Price Index, expert says.

New research designed to measure the accuracy and validity of a trio of tools designed to assess quality of life in psoriatic arthritis patients indicates that none are comprehensive enough to be used alone and suggests that caregivers use 2 of the assessments in tandem.

Study results suggest that a treatment for psoriasis and multiple sclerosis may induce a dangerous adverse effect, particularly in women. The finding is potentially important, because while treatment with fumaric acid esters has been around for more than 40 years, it is now being used more widely in the United States, Germany, and other areas.

New research clarifies the presentation and treatment of nail psoriasis for rheumatologists, dermatologists and general practitioners.

New treatment guidelines for non-radiographic axial spondyloarthritis call for treatment with TNF blockers if NSAIDs fail.

Psoriatic arthritis is an easy diagnosis to miss, but certain clinical features can help physicians make the call.

Study shows treatment with golimumab, with or without concomitant methotrexate, reduces symptom severity and improves disease outcomes in patients with psoriatic arthritis. However, adding methotrexate may increase the efficacy of golimumab.

Rheumatologists and dermatologists need to team up on treating psoriasis.

The first level in management of nail psoriasis is patient education.

Research highlights success in treat-to-target and early treatment of psoriatic arthritis.

Recent research has discovered evidence potentially supporting a parent-of-origin effect in psoriatic disease.

I'm always fascinated by the Medscape physician reports every year and seeing how unhappy physicians are. How burnt out they are. How dissatisfied with their careers they are.

Patient with autoimmune diseases, like psoriasis, and infected with herpes zoster – commonly known as shingles – have a 50% higher risk of suffering a stroke.

It is generally well-understood that smoking cigarettes exacerbates symptoms of psoriasis. But recent study results clarify and strengthen the link between smoking and the development of psoriatic lesions.

A retrospective analysis of patients who underwent bariatric surgery suggests that significant weight loss significantly lessens the symptoms of psoriasis and psoriatic arthritis.

When I first started seeing patients on my own, I would get annoyed when patients came in with printouts from WebMD, Health.com, or the dreaded Wikipedia.

In a phase 3 study, ixekizumab showed significant, clinically meaningful improvements of disease activity and physical function for patients with psoriatic arthritis.

Blocking IL-23p19 with an investigational Boehringer-Ingelheim compound called BI 655066 got better results than ustekinumab (Stelara/Janssen) in patients with moderate to severe plaque psoriasis

In psoriatic arthritis, biomechanical forces could play a role in the exacerbation or initiation of disease. Research shows that surgical weight loss lessens psoriasis and psoriatic arthritis symptoms.

Patients who had bariatric surgery and lost weight were likely to also see improvement in symptoms of psoriasis and psoriatic arthritis, NYU Langone researchers report.

A multinational group known as GRAPPA has compiled a new set of treatment recommendations for psoriasis and psoriatic arthritis.

Systemic bone loss can occur in psoriatic arthritis, but it doesn’t always show up using traditional scanning methods, new research finds.