Spondyloarthritis

Recent research has discovered evidence potentially supporting a parent-of-origin effect in psoriatic disease.

I'm always fascinated by the Medscape physician reports every year and seeing how unhappy physicians are. How burnt out they are. How dissatisfied with their careers they are.

Patient with autoimmune diseases, like psoriasis, and infected with herpes zoster – commonly known as shingles – have a 50% higher risk of suffering a stroke.

It is generally well-understood that smoking cigarettes exacerbates symptoms of psoriasis. But recent study results clarify and strengthen the link between smoking and the development of psoriatic lesions.

A retrospective analysis of patients who underwent bariatric surgery suggests that significant weight loss significantly lessens the symptoms of psoriasis and psoriatic arthritis.

When I first started seeing patients on my own, I would get annoyed when patients came in with printouts from WebMD, Health.com, or the dreaded Wikipedia.

In a phase 3 study, ixekizumab showed significant, clinically meaningful improvements of disease activity and physical function for patients with psoriatic arthritis.

Research highlights a need for closer partnerships between physicians and patients to set shared treatment goals.

Results from the MEASURE 1 trial suggest that about 80% of patients with ankylosing spondylitis had no radiographic progression in the spine on x-ray assessment after a 2-year course of secukinumab.

Blocking IL-23p19 with an investigational Boehringer-Ingelheim compound called BI 655066 got better results than ustekinumab (Stelara/Janssen) in patients with moderate to severe plaque psoriasis

Patients who had bariatric surgery and lost weight were likely to also see improvement in symptoms of psoriasis and psoriatic arthritis, NYU Langone researchers report.

Study results show treatment with tofacitinib imrpveos symptoms in patients with ankylosing spondylitis.

A multinational group known as GRAPPA has compiled a new set of treatment recommendations for psoriasis and psoriatic arthritis.

An analysis of 35 years of cohort data provides fresh information about the biggest risk factors for cardiovascular disease in patients with psoriatic arthritis.

A meta-study of randomized controlled trials indicates that older TNF-inhibitors such as etanercept or infliximab treat psoriatic arthritis more effectively than newer TNF-inhibitors.

Researchers report that tailored, computer-based training and interventions can increase the effectiveness of health promotion programs for many workplaces.

Secukinumab was more effective than placebo in patients with psoriatic arthritis in a second phase 3 trial, strengthening the case for approval as a treatment for the disease.

A German cohort study in Archives of Dermatological Research found that antipsoriatic drugs for treatment of moderate-to-severe psoriasis are generally safe over the long-term.

An increased risk of cardiovascular disease is present in early rheumatoid arthritis and early spondyloarthritis, new research shows.

Longer intervals between injections of anti-TNF drugs in patients with psoriatic arthritis is "safe, effective, cost-effective, and facilitates patient compliance," according to researchers.

Individuals afflicted with psoriasis and psoriatic arthritis are also at higher risk for new-onset migraines.

Ankylosing spondylitis appears to carry an increased risk of vascular mortality, Canadian researchers report.

A study of patients undergoing total hip arthroplasty found that patients with psoriatic arthritis face no greater risk of poor outcomes than patients who get hip replacements because of osteoarthritis.

A study in PLOS One found evidence that fat metaplasia in sacroiliac joints (SIJ) is significantly associated with spinal progression for axial spondyloarthritis (axSpA).

Adalimumab gets new indication for hidradenitis suppurativa.

Regulators in the UK have decided not to recommend apremilast as an alternative to DMARD therapy in patients with psoriatic arthritis.

Researchers have found further links between vitamin D deficiency and chronic inflammatory rheumatic diseases such as psoriatic arthritis.

Half of the patients with psoriatic arthritis enrolled in a trial of etanercept continued responding to the medication and complying with treatment guidelines for more than 5 years.

A recent study suggests that patients with ankylosing spondylitis (AS) have a higher incidence of obstructive sleep apnea syndrome that increases with the severity of cervical vertebral involvement. A separate study published on the same day suggests that specific exercise regimens may be beneficial for patients with AS.

New research suggests that a 10-second self assessment might provide nearly as much information about psoriatic arthritis case progression as complex tests that generally require either require laboratory results or formal joint-by-joint evaluation.