Hypertension

A pooled analysis of data from the RADIANCE-HTN TRIO, RADIANCE-HTN SOLO, and RADIANCE II trials provide a comprehensive overview of the potential reductions in blood pressure possible with renal denervation.

Data from the Diuretic Comparison Project suggests chlorthalidone did not provide a reduction in cardiovascular risk or all-cause mortality compared with use of hydrochlorothiazide in older patients with hypertension.

An analysis of nationally representative data from AHA 2022 suggests most older adults in the US with hypertension were not receiving adequate treatment intensification set forth in US and international guidelines.

An analysis comparing prepandemic blood pressure management against blood pressure management during the first months of the COVID-19 pandemic details rising blood pressure and declining blood pressure control coinciding with the implementation of lockdown and stay-at-home orders.

The beneficial effect of intensive BP control on cardiovascular and all-cause mortality was attenuated during 4.5 years of post-trial after SPRINT.

A trial of 110 women suggests use of nifedipine extended-release leading up to delivery could reduce risk of severe hypertension events among pregnant women with preeclampsia without increasing risk of adverse neonatal outcomes.

Sotatercept added to background therapy demonstrated significant improvement in exercise capacity compared to placebo.

Deepak Bhatt, MD, MPH, discusses the long-term follow-up data from SYMPLICITY HTN-3 from TCT 2022 and explores the prospect of renal denervation outside of clinical trial settings.

Mother's who follow the DASH dietary pattern experience better sleep health for themselves and their infants, according to new study.

A new study from the AHA's Hypertension Scientific Sessions provides an overview of the potential population-level benefit of behavior modification, including adherence to a DASH diet, on CVD events and mortality among patients with stage 1 hypertension.

Mean systolic blood pressure increased by 5.09 mm Hg immediately after implementation of automated monitoring.

Our cardiology month in review spotlights the most popular content from the past month. The top content from August 2022 includes new antithrombotic guidance from CHEST, USPSTF recommendation statement on statin use in primary prevention, and coverage of ESC 22, including DELIVER, TIME, and other late-breaking data.

Although the Hygia study suggested nighttime dosing could increase the benefit of risk reduction obtained from antihypertensive medications, the TIME study found no significant improvement in risk reduction afforded by nighttime dosing as compared to morning dosing of medication.

An analysis of more than 25,000 years of patient data details a U-shaped association between HDL-C levels and cardiovascular risk among adult men with high blood pressure.

Results of the HOME BP study suggest a linked smartphone application combined with standard blood pressure monitoring did not result in superior blood pressure reductions than a standard approach.

Mean age of hypertension diagnosis was 4 - 5 years earlier among Black and Hispanic adults vs White adults between 2011 and 2020.

Dr. Gregory Weiss provides perspective on a recent study suggesting women with gestational hypertension were at an increased risk of chronic hypertension later in life.

An analysis of data from a single center in Switzerland from a 15-year period details the prevalence of undiagnosed major risk factors among patients admitted with acute ischemic stroke, suggesting 67.7% present with at least 1 undiagnosed risk factor.

The investigators labeled pre-existing glaucoma, high preoperative intraocular pressure, and combined keratoplasty with removal or exchange of an intraocular lens were definitely associated with an increased risk.

New research suggests cumulative exposure to PFAS could increase risk of incident hypertension by 71% among midlife women.

Uninsured adults with low income in nonexpansion states experienced worse access and cardiovascular risk factor management compared to insured adults.

A systematic review and meta-analysis of more than 70 RCTs details a J-shape dose-response relationship between omega-3 fatty acid consumption and blood pressure, with 2-3 grams per day considered the optimal dose for blood pressure lowering.

The media campaign to improve aspirin use included billboards, radio ads and print articles, in addition to a dedicated website.

An analysis of data from more than 11,000 patients in China suggests arterial stiffness could be a better predictor of type 2 diabetes risk than other traditional risk factors, such as hypertension.

Among patients with early-onset AF, the presence of disease-associated rare variants in CM and arrhythmia genes was associated with a 1.5-fold higher risk of mortality over 10 years.

Targeting a blood pressure of less than 140/90 mm Hg was associated with better pregnancy outcomes than reserving treatment for severe hypertension.

After adjustment for known cardiovascular risk factors, investigators found women with a hypertensive disorder of pregnancy, including preeclampsia and gestational hypertension, during their first pregnancy had a 63% greater risk of future cardiovascular disease compared to women with normotensive pregnancies.

There was no statistically significant difference in mean systolic blood pressure for the self-monitoring groups vs the usual care group.

Treating 100 older patients (≥60 years) with hypertension for approximately 3 years would prevent 1 major adverse cardiovascular event.

The rate of long-term survival after 10 years in patients surviving the initial hospital stay after OHCA was between 62% and 64%.