November 16th 2024
Reducing systolic blood pressure to less than 120 mmHg lowered the risk of major cardiovascular events for most people with diabetes in the BPROAD trial.
October 30th 2024
A decade after bariatric surgery, most teens maintained weight loss and reduced obesity-related conditions such as type 2 diabetes and hypertension.
October 21st 2024
Novo Nordisk will present more detailed data in 2025 and plans to file for an expanded label for Rybelsus for this population.
October 15th 2024
SGLT2 inhibitors appeared effective in improving hepatic inflammation and fibrosis indices in patients with type 2 diabetes and suspected MASLD.
October 6th 2024
Our September 2024 monthly recap in endocrinology spotlights regulatory updates, new guidelines, and the latest episodes of Diabetes Dialogue.
Ertugliflozin Lowers UA, Improves Gout Outcomes in People With Type 2 Diabetes and ASCVD
There were no differences in the treatment effect of ertugliflozin on gout-related outcomes in subgroups based on eric acid quintile or other baseline characteristics.
FDA Clears Eversense 365, Marking First 1-Year CGM Option in Diabetes
The FDA has approved the Eversense 365, the world’s first 1-year continuous glucose monitor, with US availability expected in late 2024.
GLP-1 RA Linked to Lower Risk of Cirrhosis Development in Patients with MASLD
A new study found glucagon-like peptide 1 receptor agonist use was associated with a lower risk of cirrhosis complications for patients with MASLD who did not have cirrhosis.
Endocrinology Month in Review: August 2024
The endocrinology month in review for August 2024 spotlights 6 pieces of major pipeline news or regulatory announcements as well as multiple episodes of Diabetes Dialogue.
Brendon Neuen, MBBS, PhD: Expanding Evidence of Combination Therapy with GLP-1 RAs and SGLT2 Inhibitors
A meta-analysis shows GLP-1 RAs and SGLT2 inhibitors offer distinct cardiovascular and kidney benefits in type 2 diabetes.
Study Finds Diabetes Complications and Mental Health Disorders Are a 2-Way Street
Michigan Medicine and U-M research finds a bidirectional link between mental health disorders and chronic diabetes complications, urging comprehensive screenings.
FDA Clears Omnipod 5 AID System for Type 2 Diabetes
FDA expands Omnipod 5 AID system for type 2 diabetes, marking the first AID system approved for both type 1 and type 2 diabetes management.
Dexcom Announces Availability, Pricing of Stelo—First OTC Glucose Sensor
Dexcom's Stelo, the first OTC glucose sensor, launches in the US on August 26, 2024, offering 15-day wear and HSA/FSA eligibility for as low as $89.99 per 2-pack.
Semaglutide Linked to Suicidal Ideation, New Study Reveals
A new study significantly demonstrated semaglutide, but not liraglutide, is associated with suicidal ideation.
HbA1c Highly Predicts NAFLD Disease Severity
A new analysis suggests HbA1c may be more informative to fatty liver disease severity than BMI, and should be included in screenings.
Diabetes Dialogue: Navigating ADCES 2024
The first of 2 episodes on ADCES 2024, this episode focuses on sessions and presentations hosts Isaacs and Bellini participated in during the meeting.
Real-World Analysis Finds Tirzepatide Offers Greater Benefit than GLP-1 RAs for Heart, Kidney in T2D
A new real-world study suggests tirzepatide provides greater reductions in mortality, cardiovascular risk, and kidney events than GLP-1 receptor agonists in type 2 diabetes.
Diabetes Dialogue: Simplera CGM and Medtronic's Partnership with Abbott
In this episode, hosts take a break from the ADCES meeting to discuss the latest news from Medtronic related to their Simplera CGM and their partnership with Abbott.
Hepatic Benefits of GLP-1 RAs Are Independent of Weight Loss in MASLD, Diabetes
Treatment with GLP-1 RAs led to improvements in weight loss, liver function tests, and liver fat in patients with diabetes and MASLD, with hepatic improvements independent of weight loss.
Medtronic Secures FDA Approval for Simplera CGM, Partners with Abbott
FDA approval for the Simplera™ continuous glucose monitor marks the company's first disposable, all-in-one CGM half the size of previous offerings.
Endocrinology Month in Review: July 2024
The July 2024 endocrinology month in review recaps a pair of regulatory updates, multiple studies on incretin therapies, and the most recent episodes of our flagship diabetes podcast, Diabetes Dialogue.
Study Finds Semaglutide Can Reduce Risk of Tobacco-Related Healthcare Use
New study finds semaglutide may reduce smoking urge in type 2 diabetes patients, decreasing tobacco use disorder medical encounters by up to 32%.
Surge in New GLP-1 Prescriptions Driven by Semaglutide's Popularity, Study Shows
An analysis using records from 40 million US patients highlights the surge in new GLP-1 receptor agonist use, with semaglutide dominating new prescriptions since 2020.
Poor Sleep Duration in Type 2 Diabetes Tied to Greater Microvascular Disease Risk
A study found individuals with type 2 diabetes who received less than 7 hours of sleep had 2.6 increased odds of microvascular disease.
Diabetes Dialogue: CATALYST Trial and Hypercortisolism in T2D, with John Buse, MD, PhD
In this episode, John Buse, MD, PhD, discusses the background, expected prevalence, reaction to results, and the importance of the second part of the CATALYST trial.
FDA Issues Complete Response Letter for Once-Weekly Insulin Icodec
The CRL cites requests related to the manufacturing process and the type 1 diabetes indication before the application review can be completed.
Semaglutide Can Preserve, Possibly Improve, NYHA Functional Class in Obesity-Related HFpEF
A STEP-HFpEF analysis suggests semaglutide 2.4 mg (Wegovy) confers benefit across the spectrum of NYHA functional class among patients with obesity-related HFpEF.
SGLT2 Inhibitor, GLP-1 RA Combination Improves Cardiovascular, Kidney Outcomes in Diabetes
Findings from a meta-analysis examining 12 trials including more than 70,000 patients with diabetes support combining SGLT2 inhibitors and GLP-1 RAs.
Tirzepatide Bests Semaglutide in Real-World Weight Loss Analysis
A study of 18,000 patients showed tirzepatide (Mounjaro) led to more significant weight loss than semaglutide (Ozempic) in adults with overweight or obesity.
Endocrinology Month in Review: June 2024
In the endocrinology month in review, we spotlight top news in the endocrinology pipeline and the most important updates from ADA 2024.
HCPLive Five at ADA 2024
Counting down the most impactful news at major medical meetings, it’s the HCPLive Five! This episode focuses on 5 updates from the 84th American Diabetes Association (ADA) Scientific Sessions.
Diabetes Dialogue: ADA 2024 Diabetes Technology Recap
In this episode, hosts recaps their picks for top diabetes technology-related updates from ADA 2024, including news from Omnipod, MiniMed 780G, and the Tandem mobi.
Diabetes Dialogue: Advances in AID and CGM at ADA 2024, with Davida Kruger, NP
Davida Kruger, NP, joins the podcast to discuss updates in automated insulin delivery and continuous glucose monitoring systems from ADA 2024.
FLOW Analysis Sheds Light on Effects of Combination Therapy with GLP-1 RA and SGLT2 Inhibitor
Data on outcomes stratified according to baseline use of SGLT2 inhibitors from the FLOW trial were presented at ADA 2024.
CATALYST Raises Red Flag on Hypercortisolism in Type 2 Diabetes, with Ralph DeFronzo, MD
Ralph DeFronzo, MD, discusses the results of the first phase of the CATALYST trial and how results should influence the care of patients with difficult-to-treat type 2 diabetes.