The HCPLive conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.
Sibgha Zaheer, MD: Determining Washout Period With Fitusiran, Emicizumab Transition for Hemophilia
Zaheer discussed how this research may be used as a model to help study other therapy transitions as well.
Pavan K. (Tem) Bendapudi, MD: Large-Scale Analyses Elucidate Genetic Risk of Thrombosis
Bendapudi gave an overview of 2 studies presented at ASH 2024 from his Harvard lab.
Seema Rani, MD: Examining Sleep Health in Youth With SCD
Rani discussed an in-depth study examining quality of sleep and quality of life in children and adolescents with SCD.
Daniel Wang: A More Appropriate Ferritin Threshold is Cost-Effective for Iron Deficiency Screening
Iron deficiency is currently screened at a ferritin threshold of 15 ug/mL, well below an accepted 25 ug/mL threshold.
Kimberly A. Davidow, MD: Elucidating Risk of Autoimmune Disease in Childhood Cancer Survivors
Davidow discussed how a new cohort study has helped support findings of an older European study and the need for a prospective trial to confirm the increased risk.
Yehuda Handelsman, MD: Key Highlights, Takeaways from WCIRDC 2024
Yehuda Handelsman, MD reflects on the WCIRDC 2024’s comprehensive approach to advancing cardiometabolic care through multidisciplinary collaboration.
Yehuda Handelsman, MD: Insulin Resistance in Cardiometabolic Disease and DCRM 2.0
Yehuda Handelsman, MD highlights insulin resistance’s role in cardiometabolic disease and introduces DCRM 2.0 as a global, multi-specialty care framework.
Julia Weisinger, MD: Obinutuzumab a Promising Option for Intolerant/Refractory iTTP
Weisinger discussed findings from the largest cohort of patients with iTTP treated with Obinutuzumab.
Nathan D. Wong, MPH, PhD: Growing Role of Lp(a) in Cardiovascular Risk Assessment
Nathan D. Wong, MPH, PhD discusses the evolution of Lp(a) in risk assessment, given its role as a genetic risk factor for cardiovascular complications.
Laurence Sperling, MD: Expanding Cardiologists' Role in Obesity Management
Laurence Sperling, MD described the evolving role of cardiologists in obesity care, particularly with the increasing adoption of therapies such as GLP-1 agonists.
Laurence Sperling, MD: Multidisciplinary Strategies to Combat Obesity Epidemic
Laurence Sperling, MD shares insights into a multi-disciplinary approach to the management of obesity from the perspective of a cardiologist.
Schafer Boeder, MD: Role of SGLT2 Inhibitors and GLP-1s in Type 1 Diabetes
Schafer Boeder, MD describes the potential role and safety of adjunctive therapy, including SGLT2 inhibitors and GLP-1 agonists, for patients with T1D.
Study Highlights Real-World Mortality Rates, Factors Increasing Mortality Risk in MASH
Real-world data from 18,710 MASH patients highlight the impact of comorbidities, biomarkers, and region on mortality, with 70% of deaths CVD-related.
Machine-Learning Models Could Help ID MASH Patients Considered Candidates for Resmetirom
Machine learning models improve accuracy in detecting MASH with F2-F3 fibrosis, surpassing noninvasive tests in sensitivity, specificity, and predictive value.
Matthew J. Budoff, MD: Examining the Interplay of Coronary Calcium and Osteoporosis
Matthew J. Budoff, MD describes bridging the gap between atherosclerosis and osteoporosis through advanced Imaging techniques.
Aldosterone Dysregulation Linked to Notable Risk of Hypertension
Observational data point to aldosterone dysregulation as an underrecognized risk factor for hypertension and confirm T2D as a known risk factor.
Alice Cheng, MD: Exploring the Link Between Diabetes and Dementia
Alice Cheng, MD, discusses the impact of diabetes on cognitive function and the emerging role of diabetic drug classes in dementia care.
Orly Vardeny, PharmD, MS: Finerenone for Heart Failure with EF >40% in FINEARTS-HF
Orly Vardeny, PharmD, MS explores the efficacy of nonsteroidal MRAs in heart failure with mildly reduced or preserved ejection fraction in the FINE-ARTS trial.
Matthew J. Budoff, MD: Impact of Obesity on Cardiometabolic Health in T1D
Matthew J. Budoff, MD discusses the effects of obesity and cardiometabolic complications in the contemporary management of type 1 diabetes.
Jennifer B. Green, MD: Implementation of Evidence-Based Therapies for T2D
Jennifer B. Green, MD highlights the successful implementation of evidence-based therapies for high-risk patients with type 2 diabetes.
Ralph A. DeFronzo, MD: Noxious Nine and Mifepristone for Hypercortisolism in T2D
Ralph A. DeFronzo, MD discusses the Noxious Nine and the impact of hypercortisolism on difficult-to-control type 2 diabetes.
Matthew Weir, MD: Prioritizing Cardiovascular Risk in Chronic Kidney Disease
Matthew Weir, MD discusses how a multidisciplinary approach is reshaping CKD management, with a focus on mitigating cardiovascular events.
Tadashi Matsushita, MD, PhD: Reducing Treatment Burden in Hemophilia A
Matsushita discussed findings from the OLE FRONTIER4 study of Mim8.
Davide Matino, MD, MSc: Bringing Marstacimab Treatment to Hemophilia A and B
Matino discussed data from the phase 3 BASIS study evaluating the recently approved Hympavzi.
Mifepristone Notably Reduces HbA1c in Treatment Phase of CATALYST Trial
Patients with hypercortisolism and difficult-to-control type 2 diabetes who received mifepristone exhibited a significant HbA1c improvement in the Phase 4 trial.
Insulin Resistance Amplifies Risk of Colorectal Cancer Development
Elevated blood insulin levels and insulin resistance each contributed to an elevated risk of colorectal cancer, a new study finds.
Ben Samelson-Jones, MD, PhD: Validating Long-Term Safety of Hemophilia AAV Gene Therapy
Samelson-Jones discussed follow-up data of up to 6 years with investigations of fidanacogene elaparvovec.
Françoise Bernaudin, MD: A Decade of Follow-up Reveals allo-SCT Superiority Over SOC for Sickle Cell Anemia
Bernaudin discussed the Drepagreffe-1 and 2 studies and improvements seen over 10 years of follow-up.
Pegcetacoplan Demonstrates Control in Both C5i-Experienced and Naïve PNH
Real-world clinical data from the Adelphi PNH II Disease Specific Programme were reported at ASH 2024.
Danicopan a Safe Option for Breakthrough Bleeds in PNH
Danicopan add-on therapy demonstrated more favorable safety in the ALPHA trial than pegcetacoplan did in the PEGASUS trial in a new analysis.