Upadacitinib Achieved Clinically Meaningful Efficacy Responses in TNFi-IR Patients with RA
A post hoc subgroup analysis compared TNFi-IR patients receiving upadacitinib 15 mg once daily in 3 Phase 3 clinical trials: SELECT-BEOYND, SELECT-CHOICE, and SELECT-COMPARE.
Better Clinical Responses for Biologic Naïve AxSpA Patients Treated with Secukinumab
There were no significant safety issues in the group of patients treated with secukinumab for more than 3 years.
Medical Cannabis Use Lowers Symptom Burden for Rheumatologic Disease Patients
The results also show substantial medication substitution across prescription drug classes related to medical cannabis use.
Guselkumab Significantly Reduces Disease Activity in TNFi-IR Psoriatic Arthritis
Low levels of disease activity were achieved and increased throughout the study.
Sex Differences Found in Remission Course for Rheumatoid Arthritis Patients
The median time-to-remission was longer for women compared to men.
Opioid Use for Bothersome Pain in Rheumatoid Arthritis Could Increase Thromboembolism Risk
Social Isolation Leads to Worse Outcomes Following Low-Trauma Hip Fracture
Individuals who were socially isolated at time of fracture had significantly worse function, ability to participate in social roles, and depression time of fracture.
Robert Hamilton, MD: The Potential Impact of Identifying Fetal Congenital Heart Block
Hamilton and his team aim to reduce intensive and often unnecessary screening, including weekly fetal cardiac ultrasounds, via autoantibody identification.
Robert Hamilton, MD: Autoantibodies Associated with Fetal Cardiac Events
The number of autoantibodies and congenital heart block pregnancies expanded to approximately 30 different autoantibodies to different targets near term.
Upadacitinib Provides Marked Improvements in Rheumatoid Arthritis Datapoints
The results show improvements in RAPID3, pain, fatigue, and morning stiffness at weeks 8 and 12 among patients treated with upadacitinib.
Older Age, Male Sex Linked to More Severe COVID-19 Outcomes in Rheumatology Patients Treated With Secukinumab
Patients with ankylosing spondylitis generally had more favorable outcomes compared to those with psoriasis or psoriatic arthritis.
Stimulating PD-1 Medication Shows Promise Treating Rheumatoid Arthritis
In data presented during ACR, investigators find peresolimab could be an effective treatment for adult patients with rheumatoid arthritis.
Patient B-Cell Counts at Time of Vaccine Influence COVID-19 Antibody Response
Patients who are treated with B cell depletion therapies show that their B cell count at time of vaccination can impact their COVID-19 antibody response.
Inflammatory Rheumatic Disease Linked to Reduced mRNA COVID-19 Vaccine Response
An assessment of a rheumatic disease cohort shows Spike protein antibody response is significantly decreased in vaccinated patients, and may vary by treatment.
Mithu Maheswaranathan, MD, Speaks About Low Health Literacy in SLE Patients
Lower health literacy has been found to be associated with worsened health outcomes for patients with systemic lupus erythematosus (SLE).
Adverse Pregnancy Outcomes Remain Significant in Women with Systemic Sclerosis
Fetal deaths associated with the rheumatic disease have been on the decline, but increased risks persist nonetheless.
Women, Alcohol Drinkers Are at Greater Risk of Methotrexate Side Effects
Alopecia and nausea risk may be more easily identified in patients initiating methotrexate for rheumatoid arthritis.
Jonathan Vela, MD: CBD Shows No Effect in Patients with Chronic Pain
A study presented at ACR 2021 found that CBD had no significant effect on pain intensity in patients with hand osteoarthritis or psoriatic arthritis.
Guselkumab Safety Remains Consistent in Psoriasis, Psoriatic Arthritis
An assessment of data from the DISCOVER and VOYAGE trials show the IL-23 inhibitor provides similar safety profiles in patients with either psoriatic disease.
Romosozumab FDA Label May Have Reduced Cardiovascular Risks in Osteoporosis Patients
Interim data from a post-marketing analysis suggest a boxed label warning for the drug in 2019 may have limited high-risk patients taking the biologic therapy.
Pediatric Arthritis Linked to Households with Lower Income, Education
A cross-sectional analysis suggests patients with worse social risk scores are significantly more likely to be impacted by juvenile idiopathic arthritis.
Nathan den Broeder, MSs: Finding the Right Dose of Rituximab for Rheumatoid Arthritis
This study shows that many patients with rheumatoid arthritis can use a dose lower than 1000mg and still see results.
Jonathan Vela, MD, Decides it's Time to Examine CBD Treatment for Chronic Pain
With the popularity of CBD growing in Denmark, Jonathan Vela, MD, examined the effectiveness of CBD treatment on hand osteoarthritis and psoriatic arthritis.
Rituximab Linked to Worse COVID-19 Vaccine Response than Immunosuppressants
More data from ACR 2021 evidences the risk of minimal response to mRNA vaccines in autoimmune disorder patients on rituximab.
Jing Cui, PhD, Discusses Next Steps for Risk Prediction Models for SLE
In this video interview, Dr. Jing Cui explains what the next steps could be for the risk prediction models of systemic lupus erythematosus.
Ehizogie Edigin, MD: Outpatient Care Helps Reduce Hospitalizations for SLE Flare
In this video interview, Dr. Edigin talks about the importance of outpatient care in reducing hospitalizations for SLE flare.
Nathan den Broeder, MSs: Treating Rheumatoid Arthritis with Lower Doses of Rituximab
Nathan den Broeder, MSs, shares the findings of his study at the ACR 2021 Convergence.
Jing Cui, PhD: Identifying Risk Factors for Systemic Lupus Erythematosus
Research presented by Dr. Jing Cui at ACR 2021 Convergence identified significant risk factors for systemic lupus erythematosus in a risk prediction model study.
Ehizogie Edigin, MD, Discusses Racial Disparities Found in SLE Study
Research results shows that while overall hospitalization for SLE flare decreased, it increased among African American patients.
Jing Cui, PhD: SLE Risk Assessment Among Nurse Cohorts
Dr. Jing Cui speaks about how she examined lifestyle and environmental factors as well as genetic risk to assess risk of systemic lupus erythematosus.