Article

Endocrine Case Report: Weak and Thirsty

This endocrine case report from Brady Pregerson, KMD, features a woman in her mid-30s with a history of cerebral astrocytoma status post radiation therapy presenting with generalized weakness, a gradual onset generalized headache, and excessive thirst. Can you determine the correct diagnosis?

History of Present Illness:

A patient in their mid-30s with history of cerebral astrocytoma status post radiation therapy presents to the hospital with generalized weakness, a gradual onset generalized headache and excessive thirst. She denies any recent fevers or any nausea/vomiting/diarrhea, black or bloody stool or other complaints. There have been not seizures, falls or injuries.

Vital Signs & Physical Exam:

Vital signs are normal except for mild blood pressure elevation. The physical exam is essentially normal and the oropharynx does not look dry.

Initial Diagnostic Testing:

CBC: Normal

Chem-7: The sodium is very high at 163 with elevated chlorine as well. Other values are essentially normal.

Imaging: Brain CT showed no significant change from baseline.

What is the most likely diagnosis?


Related Videos
| Image Credit: X
Ahmad Masri, MD, MS | Credit: Oregon Health and Science University
Ahmad Masri, MD, MS | Credit: Oregon Health and Science University
Stephen Nicholls, MBBS, PhD | Credit: Monash University
Marianna Fontana, MD, PhD: Nex-Z Shows Promise in ATTR-CM Phase 1 Trial | Image Credit: Radcliffe Cardiology
Zerlasiran Achieves Durable Lp(a) Reductions at 60 Weeks, with Stephen J. Nicholls, MD, PhD | Image Credit: Monash University
Gaith Noaiseh, MD: Nipocalimab Improves Disease Measures, Reduces Autoantibodies in Sjogren’s
4 experts are featured in this series.
4 experts are featured in this series.
A. Sidney Barritt, MD | Credit: UNC School of Medicine
© 2024 MJH Life Sciences

All rights reserved.