Mark Nestor, MD, PhD: What’s Coming Up Next in Dermatology?

In this interview segment, Mark S. Nestor, MD, PhD, spoke about some of the major points covered in his latest talk ‘What’s Coming Up Next?’ at the 2023 Fall Clinical Dermatology Conference in Las Vegas.

Nestor is known for his work as a voluntary associate professor for the department of dermatology and cutaneous surgery at the University of Miami Miller School of Medicine. Additionally, Nestor works as director of the Center for Cosmetic Enhancement and of the Center for Clinical and Cosmetic Research in Aventura, Florida.

In his discussion with the HCPLive editorial team, Nestor kept to the most important elements of his conference talk.

“Number 1 is we have a lot of new devices, not only for aesthetics, but to treat some of our conditions,” Nestor explained. “New devices to treat psoriasis, new devices to treat acne. And they're very effective, especially in times where we're having difficulties with getting some of our medications or with the side effects, etc. Some of these devices can really help us treat our patients.”

Nestor highlighted the long-pulsed 1064 nm Nd:YAG laser and the 1572 laser for patients with acne.

“There's also evidence presented that the short-pulse YAG laser can work very well with psoriasis,” he said. “So you have these new indications for aesthetics as well as treating our clinical patients. So that's 1 area that's really exciting. The second area is what I'll call this new aspect of regenerative medicine.”

When asked about some of the new products available for dermatologists, Nestor explored some of the ones covered in his talk.

“The first is some of the oral and medical foods and what are the next generation of supplements that can really help the skin,” Nestor said. “There are a few of them that work really well with this. The first 1 is what we call a flavonoid, and a flavonoid comes from citrus and other things. This flavonoid is called diosmin…We've had really incredible results treating really conditions that don't work very well with normal treatments like stasis dermatitis. Because it works and it reacts on helping strengthen the chronic vascular disease venous system and helps the circulation.”

He added that diosmin can help inflammation, noting that strong results with that have been observed.

“What's really exciting though is in addition to the clinical aspects, for problems that are more aesthetic but also clinical, such as Schamberg disease, we can see some really nice benefits with flavonoids like the diosmin. Even for senile purpura, there's evidence and data that this is very effective. This is one of these new treatments that are medical foods.”

Another flavonoid product Nestor commented on was genistein, which he noted comes from soybeans.

“We have some great data that it really can help on sun-exposed skin to not only reverse some of the changes but to prevent long term skin cancers, from that perspective,” Nestor said. “And there's a beauty aspect to that because genistein has been shown in studies to affect even lines and wrinkles, and sun damage especially in postmenopausal individuals.

To find out more about some of the latest updates discussed by Nestor, view the full interview segment above.

The quotes used here were edited for clarity purposes.