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(1) Questionable efficacy of knee injections, (2) a dramatic increase in the prevalence of osteoarthritis, and (3) a promising molecular biomarker.
References1. Bedard NA, DeMik DE, Glass NA, et al. Impact of clinical practice guidelines on use of intra-articular hyaluronic acid and corticosteroid injections for knee osteoarthritis. J Bone Joint Surg Am. 2018;100:827-834. doi: 10.2106/JBJS.17.01045.2. Park J, Mendy A, Vieira ER. Various types of arthritis in the United States: prevalence and age-related trends from 1999 to 2014. Am J Public Health. 2018;108:256-258. doi: 10.2105/AJPH.2017.304179.3. Rivas F, Zahid OK, Reesink HL, et al. Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor. Nature Communications. 2018;9:1037. Published March 12, 2018.