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RA Quiz: What if methotrexate fails?

Author(s):

Ingrid Torjesen

Methotrexate is considered first-line therapy for rheumatoid arthritis, but if this fails to control symptoms, it is time to consider a second-line therapy. TNF inhibitors and IL inhibitors are options, but which to choose? Learn more in this quiz.

In general, what drug does the American College of Rheumatology recommend be considered first for patients with moderate or high disease activity despite DMARD therapy: a TNF inhibitor or a non-TNF biologic such as an IL inhibitor?


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