Research Reveals Relationship Between Rosacea and Glioma Risk

Rosacea has been linked to a significantly increased risk of developing glioma.

According to research published in JAMA Dermatology, Alexander Egeberg, MD, PhD, University of Copenhagen, Hellerup, Denmark, and colleagues conducted a national study from 1997 to 2011.

To analyze the hypothesized relationship between rosacea and glioma, Egeberg and team assessed data for 68,372 patients with rosacea and 5,416,538 in the control population.

Egeberg and colleagues discovered the incidence rate of glioma per 10,000 person-years was 3.34 in the control population and 4.99 in the group afflicted with rosacea.

The primary analysis indicated the adjusted incidence rate ratio of glioma in rosacea patients was 1.36.

“Rosacea was associated with a significantly increased risk for glioma in a nationwide cohort. This association may be mediated, in part, by mechanisms dependent on matrix metalloproteinases. Increased focus on neurologic symptoms in patients with rosacea may be warranted,” concluded the authors.