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(1) Menopause worsens RA symptoms; (2) obesity increases disease activity in women with lupus; and (3) signs of cardiac disease appear early in SLE.
References1. Mollard E, Pedro S, Chakravarty E, et al. The impact of menopause on functional status in women with rheumatoid arthritis. Rheumatology. 2018;57:798-802. doi: 10.1093/rheumatology/kex526.2. Patterson S, Schmajuk G, Jafri K, Yazdany J, Katz P. Obesity independently associates with worse patient-reported outcomes in women with systemic lupus erythematosus. Arthritis Care Res. 2018 May 8. doi: 10.1002/acr.23576.3. Guo Q, Wu LM, Wang Z, et al. Early detection of silent myocardial impairment in patients with new onset drug-naïve systemic lupus erythematosus - a three-center prospective study (Myocardial Impairment in New Onset SLE). Arthritis Rheumatol. 2018 Aug 2. doi: 10.1002/art.40671.