Kenny Walter

In part A of the trial, 60% of patients treated with dupilumab weekly met the primary endpoint of histologic remission, compared to 5% of the placebo group.

There was a decrease in relapse observed for low-risk participants, but not high-risk individuals.

With the population aging, there is a need for new treatments in nephrology.

There was no differences observed in total weight loss at both 6 and 18 months in the fecal microbiota transplantation and placebo groups.

Some in the industry expect the Adderall shortage to possibly last until March 2023.

Serotonin syndrome occurred in less than 0.5% of patients, while the number of serotonin syndrome cases was fewer in the antidepressant group.

The results show significant LSM relative reductions compared to pooled placebo in aspartate aminotransferase for pegozafermin 3 mg once weekly, 27 mg once weekly, and 36 mg once every 2 weeks.

TRD episodes resulted in more inpatient bed-days and lost workdays compared to non-TRD episodes.

The receipt of DAA treatment within 1 year was 7% for patients entering the cohort in 2014, compared to 33% in 2015, 53% in 2016, and 56% in 2017.

The total duration of sleep increased from 9 hours 8 minutes prior to the pandemic to 9 hours 54 minutes during school closures in Taiwan.

Both shorter and longer sleep duration were associated with fewer academic enables and lower academic skills and math grades.

The investigators also found an increase in the proportions of monthly hospitalizations during the pandemic for a number of disorders, including anxiety, depression, and suicidality or self-injury.

The treatment rate decreased from 64.8% to 61.2% after 2018.

The most common thrombophilia types were heterozygosity for factor V Leiden, prothrombin 20210A mutation, and protein S deficiency.

In a late-breaking abstract presented during ASH 2022, investigators found patients treated with PTCy had a significantly lower hazard of GRFS than the standard therapy group.

The treatment was superior in various secondary endpoints, included transfusion avoidance, changes from baseline in hemoglobin level, FACIT-F scores and ARC, and the rate of clinical BTH.

Spleen size can vary significantly in pediatric patients with sickle cell anemia.

The results show the mean change from baseline in PKDD was ‒7.19 for M/M patients, ‒4.58 for P/M patients, and ‒3.94 for mitapivat patients.

Every patient in the study was VOC-free at the time of the data cut.

The observed heterogeneity between BP-CMML cases suggested distinct clinicopathological phenotypes and the investigators integrated clinical metadata with blast immunophenotype with 59 independent features.

In 2021, the USPSTF changed guidance on colorectal cancer screenings, reducing the recommended age of a colonoscopy from 50 to 45 years.

Pauk Feuerstadt, MD, discusses some future applications of RBX2660.

Individuals living in lower-income situations were also more likely to have vision impairment, use eye care services less, and have lower adherence to eye examinations.

There was also higher neutralizing antibody titers against BA.4/5 with a lower hazard risk in the group with a breakthrough infection.

Prometheus Biosciences is expected to begin phase 3 trials for the treatment in 2023.

At week 16, the static Physician’s Global Assessment scores were significantly greater in the mirikizumab group than in the placebo group.

The results show female patients were more likely to be diagnosed with any adverse event.

Sustained virologic response was reached by 98% of the study at 12 weeks following the conclusion of treatment and remained consistent among genotype, HCV RNA values, fibrosis stage, and the subgroup of interest.

They also found no statistically significant associations found for specific cardiovascular outcomes in relation to cardiac arrest or arrhythmias, cerebrovascular diseases, or myocardial infarction.

They also found a high-risk perception of HBV was associated with the willingness to be vaccinated against hepatitis B in participants from either province.