Kevin Kunzmann

In 2018, investigators confirmed that one of the staple symptoms of multiple sclerosis—white matter demyelination—isn't always consistent.

The seemingly complicated maneuvers of getting patient’s cholesterol better can be resolved with common sense. What’s best for the patient?

Since the PCSK9 inhibitors were approved for cholesterol management by the FDA in 2015, they have been frequently compared.

Healthcare provider employment opportunies have risen 7.1%—an increase from 2017's reported rate of 5%. Where are the jobs in most demand?

The non-invasive device is now the first and only FDA product approved for the prevention of cluster headache.

How the opioid epidemic and high drug prices have brought the hepatitis C burden onto a younger population in 2018.

Currently available anemia therapies only provide benefit for about half of patients with a lower-risk myelodysplastic syndromes (MDS)-related condition—and about one-quarter of such patients dependent on red blood cell transfusions.

The odds ratio of patients on the therapy reaching ≥33% RBC transfusion burden reduction was 5 times greater than those on placebo.

The FDA has approved amifampridine (Firdapse) tablets as the first ever treatment of the rare autoimmune disorder, Lambert-Eaton myasthenic syndrome (LEMS) in adults.

The rare disease is associated with other autoimmune conditions including small cell lunger cancer, and is estimated to be prevalent in approximately 3 million people worldwide.

Progestin compound segesterone acetate, which would be combined with testosterone, is currently marketed for the use of hormonal contraception, and for the treatment of endometriosis.

A new study found the annual top-50 ranking is a reliable indicator of cardiovascular disease mortality and patient satisfaction.

What could have been uncovered is further evidence for a progressive-onset MS phenotype characterized by acute episodic inflammatory changes.

The ACTPen was approved on the basis of a pair of clinical trials presented at the 2018 American Society for Clinical Pharmacology & Therapeutics Annual Meeting.

The septic shock therapy was approved by the FDA last December. How has it fared in its first year of real-world clinical use?

How fatty liver disease and NASH—as well as the comorbidities associated with them—highlighted this year's discussions.

According to the FDA, patients who stop the therapy are at a severe risk of symptoms worsening than previously to them even starting therapy.

The biologic AR101 was previously shown to significantly desensitize peanut allergies in a pediatric and adolescent patient population.

HRS-1 is a rare, acute complication of liver cirrhosis characterized by life-threatening and rapid progression that can end in renal failure. Terlipressin, a vasopressin analogue, could become the first therapy approved for the treatment of HRS-1 in the US.

Officials are concerned the perpetual cycle of information sharing—by both pro- and anti-vaccination parents—is creating an echo chamber in the US.

The AR101 oral therapy—a biologic designed to desensitize peanut allergies, manufactured by Aimmune Therapeutics—is anticipated to be submitted for FDA approval in the next month.

The antibacterial therapy has been indicated for forms of the disease driven by E. coli.

In analysis, the therapy plus standard immunosuppressive therapy resulted in a complete response rate 27% greater than that historically observed in patients treated with lone IST, over 6 months.

New results from a pair of phase 3 trials will be used to support AbbVie's anticipated NDA submission in 2019.

In using the EDSS and 9HPT scales as a metric for the therapy’s influence on disability risk reduction, the investigators were additionally providing context to ocrelizumab’s benefits for ambulation rates and MS-related costs.

About 21% to 74% of patients with AF will also have obstructive sleep apnea. What is one medical center doing to find these patients in their cardiology department?

A popularizing procedure among stroke centers was the basis of clinical research for the medical center, and is now improving in practice.

How surgeons' duties surround the entire invasive process, and therefore make them something closer to specialists.

A meta-analysis of more than 7 million patients confirms that just 1 instance of a concussion or mild TBI is associated with a two-fold greater risk of suicide.

Investigators praised the excellent effectiveness of both therapies, but advised care regarding the increased odds of adverse events requiring hospitalizations.