BMI and the Risk of All-Cause Mortality Among Patients with Type 2 Diabetes Mellitus
March 30th 2015Studies have identified lower-than-normal BMIs to be associated with higher mortality in comparison with normal body weight and overweight individuals in patients with coronary artery disease. This has given rise to the term "obesity paradox" in which being overweight/obese confers a survival advantage in individuals that have been diagnosed with a medical condition. Against this backdrop, this study attempted to evaluate whether there is an association between BMI and death risk among patients with type 2 diabetes mellitus.
Read More
Comparing Varenicline with and Without Nicotine Replacement Therapy for Smoking Cessation
February 2nd 2015While various behavioral and pharmacologic agents have proven to be effective and safe for continued smoking cessation, a combination of varenicline and nicotine replacement (NRT) with transdermal patches has not been shown definitively to be more efficacious than varenicline alone. In the framework of a randomized clinical trial (RCT), the present study evaluates whether a combination of varenicline with NRT improved smoking cessation rates and abstinence duration compared with varenicline alone.
Read More