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Early statin therapy in acute coronary syndromePatients who survive an acute coronary syndrome are at much higher risk of a recurrent event within the following month than patients with stable coronary syndromes. Statin therapy lowers the risk of recurrent events for many years but also reduces the risk of another event within the weeks to months following the initial acute coronary syndrome. The mechanisms that contribute to this benefit are likely related to improved endothelial function, decreased vascular inflammation, and reduced prothrombotic factors. Observation studies show an early reduction in mortality with statin therapy started before discharge from the hospital after an acute coronary syndrome.
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Benefits of Patient Connectivity in Familial Chylomicronemia SyndromeFindings from a recent study reinforce that efforts to help patients connect with other patients should be considered a vital and beneficial element in patient management.
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White-coat hypertension and progression to home hypertensionOur study aimed to clarify whether white-coat hypertension represents a transient state in the development of hypertension outside medical settings. We followed up 128 subjects with white-coat hypertension and compared their risk of progression to home hypertension with that of 649 sustained normotensive subjects. After 8 years of follow-up, subjects with white-coat hypertension had an approximately 3-fold higher risk of eventually manifesting home hypertension. We concluded that patients with white-coat hypertension should be carefully monitored.
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Noncardiovascular Effects Associated with StatinsThis review presents up-to-date evidence regarding the noncardiovascular effects associated with statins, both adverse and beneficial.
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Intensive statin therapy in acute coronary syndromeWe conducted a meta-analysis of 13 randomized controlled trials involving 17 963 subjects to determine the effect of intensive statin therapy instituted within 14 days of hospitalization for acute coronary syndrome. Results showed that early, intensive statin therapy is safe and significantly decreases cardiovascular death and recurrent ischemia following acute coronary syndrome after 6 months of treatment.
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Heparin May Reduce SARS-CoV-2 Infection RiskNew research shows the anticoagulant binds tightly with the coronavirus’ surface spike protein.
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Caring for People With Sight LossA submitted column on how to properly care for patients suffering from vision loss from the founder and medical director of Focus Clinics in London.
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How to Be the Perfect Heart PatientThere are difficult patients, and ideal patients. A cardiologist offers advice on relating to them all.
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There is No Magic Solution When It Comes to Implementing New Electronic Health Record TechnologySound research, planning, organization, and support are still the keys to success.
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Benefits of early statin treatment in patients with acute myocardial infarctionNumerous clinical trials have shown that HMG CoA reductase inhibitor (statin) therapy reduces the risk of myocardial infarction (MI), stroke, and mortality in patients with cardiovascular disease.
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High Sugar Intake During Pregnancy May Increase Pediatric Asthma RiskChildren whose mothers had a higher intake of sugar sweetened beverages and total fructose had a 19% greater chance of developing asthma in mid-childhood.
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Vernakalant: Expanding the antiarrhythmic vernacularAtrial fibrillation (AF) is the most common sustained cardiac arrhythmia, occurring in over 2% of the general population.
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Should radiofrequency ablation be first-line therapy after a first episode of symptomatic atrial flutter?Radiofrequency catheter ablation (RFA) is a cost-effective approach that has modified the treatment of patients with supraventricular tachycardia. In the Loire-Ardèche-Drôme-Isère-Puy-de-Dôme (LADIP) study, we compared RFA treatment with amiodarone therapy after the first episode of symptomatic atrial flutter. Results showed that RFA should be considered a first-line treatment, especially in elderly patients, because it has a better long-term success rate, the same risk of subsequent atrial fibrillation as amiodarone, and fewer secondary effects compared with amiodarone. Radiofrequency catheter ablation first-line therapy should be recommended in routine clinical practice, even when the atrial flutter is isolated without a previously documented atrial fibrillation episode.
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Targeted Interventions : Reengagement in Care of People Living with HIVKeeping some patients with HIV in care can be a challenge.
