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Incidence of death and MI associated with stopping clopidogrel after ACSRates of death and myocardial infarction were assessed for a national sample of acute coronary syndrome patients after stopping clopidogrel. In the first 90 days after stopping treatment, patients experienced a nearly twofold increased risk of adverse events compared with subsequent follow-up intervals for patients treated medically without stents and for patients treated with coronary stents. This suggests a possible clopidogrel rebound effect, but additional studies are needed to support this hypothesis and to identify strategies to reduce early events after clopidogrel cessation.
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Protecting privacy in the electronic era: HIPAA and HITECH mandatesIn 1890, Louise Brandeis and Samuel Warren published �¢ï¿½ï¿½The Right to Privacy�¢ï¿½ï¿½ in the Harvard Law Review, indicating private individuals were being injured by the invasions of modern-day technology
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FDA Approves Bictegravir/FTC/TAF Combination HIV TherapyThe once-daily tablet regimen was approved for the treatment of HIV-1 infection. It is the smallest INSTI-based triple-therapy STR available.
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Angiotensin-converting enzyme inhibitors in coronary artery disease and preserved left ventricular systolic functionWe performed a systematic literature review and meta-analysis to evaluate the efficacy of angiotensin-converting enzyme inhibitors in patients with coronary artery disease and normal systolic left ventricular function. Angiotensin- converting enzyme inhibitor use was associated with modest benefits, which included a reduction in cardiovascular mortality, nonfatal myocardial infarction, and revascularization rates.
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A Treatment Protocol for Opioid-Minimal Postoperative Pain ManagementA step-by-step look into how Arctic Surgery Group treats postoperative patients.
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Short on Time and Long on Flavor, Comfort Food Takes to the GrillNow that the threat of frost has finally passed (for most of us, at least), we can venture outside to dust off the grill and try a new twist on some comfort food classics, such as grill-roasted chicken and grilled asparagus.
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Pegylated Liposomal Doxorubicin (Doxil) and Drug Combinations in Multiple MyelomaCurrent treatment approaches for mutiple myeloma focus on improving progression-free and overall survival. Although five-year survival rates have increased significantly over the past ten years, the prognosis of the disease is generally poor. The availability of several promising new therapies offers clinicians treatment options to further improve response rates, especially through the development of new combination regimens.
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The Industry Insider: March 2007Additional breaking news from the biotech industry. In this issue: 1) FDA OKs Ikonisys' Bladder Cancer Test 2) Good News From China for Peregrine 3) Introgen Sees Advances on Two Fronts 4) Debiopharm Procures Cancer Therapy from Kirin Brewery
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Differences in treatment and outcomes in women with ACSMore than 1 million percutaneous coronary interventions (PCIs) are performed annually in the United States.
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Early statin treatment after acute myocardial infarctionTo evaluate whether the early use of statins would reduce cardiovascular events, we conducted a prospective, randomized trial that included 486 patients with acute myocardial infarction and normal total cholesterol levels, of whom 241 patients received statin therapy. The statin group had a lower risk of congestive heart failure and symptomatic myocardial ischemia, which indicates that early treatment with statins reduces recurrent cardiovascular events.
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Are HDL cholesterol levels clinically significant in patients with low LDL cholesterol levels?There is some debate about whether the risk of cardiovascular events associated with low high-density lipoprotein (HDL) cholesterol levels is attenuated by very low low-density lipoprotein (LDL) cholesterol levels (< 60 mg/dL), which can be obtained with statins and combination therapy.
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Partnering with Patients: Effective, Patient-Centered Care for Chronic PainA clinical health psychologist discusses how to keep a patient-centered approach for treating chronic pain in today's healthcare environment.
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How Not To Be A Difficult PatientA poster at the APA meeting, "The Difficult Patient in Psychiatric Practice," surveyed psychiatrists about which patients they considered "difficult" and why.
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Community cardiology clinics for secondary prevention of coronary heart disease and heart failure in primary careCoronary heart disease (CHD) and chronic heart failure (CHF) are common chronic conditions encountered in primary care. Studies have shown that despite a strong evidence base, these conditions are often poorly diagnosed and inadequately managed in primary care.
