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Lipoprotein(a) and coronary artery disease:The well-established causative role of low-density lipoprotein particles in atherosclerotic plaque development has led to this biomarker being a primary target of treatment in the prevention of coronary artery disease.
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NOW Initiative: Payer & Provider Collaborations in Oncology Benefits ManagementPayers recognize the need to expand benefits management for oncology but struggle to find effective solutions amid the complexity of available therapies and skepticism from oncologists, who are facing their own set of economic pressures. The National Oncology Working Group (NOW) Initiative is trying to change the sometimes adversarial relationship between payers and oncologists through a collaborative model.
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Psoriasis Linked to Protection from HIV-1Many psoriasis patients have the same gene variants as people who are not significantly affected by an HIV-1 infection.
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Roshni Patel, BSc, MCOptom: The State of Glaucoma in 2020An optometrist from Europe discusses the current state of glaucoma from identification to treatment.
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NDA for NTM Lung Disease Treatment Submitted to FDAInsmed Incorporated announced that it has submitted its New Drug Application for amikacin liposome inhalation suspension (ALIS) to the U.S. FDA.
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Patent foramen ovale closure for stroke prevention: A myriad of unanswered questionsMigraines, including those with aura, are common and generally benign, affecting between 10% and 15% of the population.
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Operating in the Global TheaterTwo American couples share what they have learned in over 20 cumulative years of treating the world's neediest patients and detail what it takes to become a successful volunteer surgeon.
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Heart failure and sudden death in patients with tachycardia-induced cardiomyopathy and recurrent tachycardiaThe effects of recurrent tachycardia after resolution of cardiomyopathy have not been thoroughly assessed. We evaluated and followed 24 patients with tachycardia-induced cardiomyopathy for more than 12 years. Our observations showed that patients with tachycardia-induced cardiomyopathy may be at long-term risk for sudden death. Surreptitious cardiomyopathy due to occult ultrastructural changes may persist. It has yet to be determined whether rapid and aggressive rate control would prevent structural damage to risk of sudden cardiac death.
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Effectiveness and Cost-Effectiveness of Diabetes Prevention among Adherent ParticipantsOver 10 years, lifestyle intervention and metformin were cost-effective or cost saving compared with placebo.
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Without the Affordable Care Act Will Medical Tourism Increase?Medical tourism could soon increase. What's that mean for US doctors?
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White-coat hypertension and progression to home hypertensionOur study aimed to clarify whether white-coat hypertension represents a transient state in the development of hypertension outside medical settings. We followed up 128 subjects with white-coat hypertension and compared their risk of progression to home hypertension with that of 649 sustained normotensive subjects. After 8 years of follow-up, subjects with white-coat hypertension had an approximately 3-fold higher risk of eventually manifesting home hypertension. We concluded that patients with white-coat hypertension should be carefully monitored.
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Raise Your Hand to Stop Diabetes®In honor of Diabetes Awareness Month, the ADA put together video clips of health care professionals pledging to stop diabetes.
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The HITECH Act Is ConstitutionalArguments that the EHR-implementation incentives under the HITECH Act are unconstitutional fail for a variety of reasons.
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The cost of failureWhen considering the article by Goldberg and colleagues, it seems reasonable to request a change in the title to "Survival after the diagnosis of  heart failure."
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Tardive Dyskinesia: Clues to the Diagnosis and TreatmentTardive dyskinesia is a common problem associated with the long-term use of potent antipsychotic drugs. It has become less common with the increased use of the newer atypical antipsychotic medications. The condition is manifested by abnormal orofacial, extremity, and sometimes trunk movements. Decades after it was first identified, our understanding of the pathophysiology of tardive dyskinesia remains incomplete, and currently no definitive treatment is available. Encouraging advances in recent years point to promising new treatment options. This article discusses factors that may predispose to tardive dyskinesia as well as the latest developments in treatment.
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Alcohol consumption in men with hypertensionWe assessed the association between the incidence of coronary heart disease and alcohol consumption among hypertensive men enrolled in the Health "Professionals" Follow-Up Study. Moderate alcohol consumption (1 to 2 drinks per day) was associated with a lower risk of myocardial infarction, as in the general population, but was not associated with the risks of stroke, total mortality, or mortality from cardiovascular causes. These results show that men with hypertension who drink moderately may not need to change their drinking habits.
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How do cardiac and noncardiac conditions affect survival after ICD implantation?The benefits of implantable cardioverter-defibrillators (ICDs) have been shown in randomized clinical trials. The factors that affect the risk–benefit ratio in a community setting, however, have not been evaluated.
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Inflammation, heart failure, and mortality in survivors of acute myocardial infarctionWe prospectively studied the relationship between C-reactive protein, obtained within 12 to 24 hours of symptom onset, and long-term risk of death and heart failure in survivors of acute myocardial infarction. The risk of death and heart failure increased progressively with increasing quartiles of C-reactive protein. We found a graded positive relationship between C-reactive protein levels and post-discharge mortality and heart failure.
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Treat-and-Extend Regimen Proves Preventive of Long-Term Vision Loss in AMDThese regimens can also ensure the maintenance of visual acuity levels that can keep patients self-sufficient in real-world scenarios, such as driving, reading, and recognizing faces.
