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Advances in the Treatment of Diabetic Kidney DiseaseOn this episode of MEDcast, Diana Isaacs, PharmD, BCPS, BC-ADM, CDCES, and Natalie Bellini, DNP, FNP-BC are joined by Dr George Bakris to discuss the latest advances in treatments and comprehensive care for patients with diabetes and chronic kidney disease.
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Managing Oral Mucositis in Patients With CancerOral mucositis is a costly consequence of cancer therapy that can impede the efficacy of anticancer therapy. Simple preventive measures can greatly improve the patient�s outcome and quality of life.
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Concerns about Pain Guidelines: When Strong Claims Follow from Weak EvidenceThe development of clinical medical-practice guidelines is a difficult and arduous process. Experts in various disciplines volunteer many hours of their time for medical research reviews and analyses and meetings with fellow guidelines-panel members, and painstakingly writing and reviewing the final report. However, there are many concerns about the quality of medical research serving as a basis for those guidelines.
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Serial biomarker measurements in chronic heart failureCardiac troponin T (cTnT) and B-type natriuretic peptide (BNP) have been used to estimate prognosis in heart failure. However, most studies have evaluated decompensated patients using single measurements. To determine the value of serial measurements, we evaluated 190 stable chronic heart failure patients every 3 months during 2 years.
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Health Reform in the Obama Era: The Case for Heart and Stroke ResearchSeveral beneficial goals should be considered as the nation contemplates health reform: (1) increase congressional awareness of the importance of heart and stroke research; (2) increase public awareness of the importance of heart and stroke research; and (3) increase funding for federal heart and stroke research.
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Taking the Guesswork Out of Concussion TestsNew technology uses the eyes to assess brain injuries in student athletes.
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The A-Z Business WireThe latest business and financial biotech news. In this issue: 1) Adherex Buys Back GSK's Rights to Failed Cancer Drug 2) Archemix and Merck Partner on Aptamer-Based Cancer Therapeutics 3) CEL-SCI Receives $15 Million Commitment for Cancer Drug Manufacturing Facility 4) Genentech and Seattle Genetics Ink Deal Potentially Worth $860 Million 5) Dana-Farber Cancer Institute Launches $1-Billion Campaign
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Are Butter and Full Fat Foods Safe?This was a systemic review and meta-analysis of randomized control trials regarding the relationship between dietary fat consumption, serum cholesterol levels, and subsequent coronary heart disease development.
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Multivessel CAD in ACS patients: Four important implicationsThe article by Schwartzman and Brener (page 33) has 4 important implications for the treatment of acute coronary syndrome (ACS) patients who are found to have multivessel coronary artery disease (CAD) during diagnostic coronary angiography.
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Amiodarone use and permanent pacing for atrial fibrillation: Are there differences between the sexes?Among patients with atrial fibrillation, amiodarone (Cordarone, Pacerone) is the most useful drug for the preservation of sinus rhythm.1-3 Although amiodarone carries a well-known risk of potentially serious noncardiac toxicities, perhaps less well recognized is its major cardiovascular side effect of bradycardia.
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New Framingham Heart Study global cardiovascular risk instruments: Helping physicians optimize their patients' cardiovascular careWhile most patients are concerned about their risk for myocardial infarction, it is important to remember that the risk factors for death from all cardiovascular diseases, including stroke, peripheral arterial disease, and coronary artery disease, are similar.
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What you get out depends on what you put inIn general, physicians are very data driven. They are trained to read, interpret, and form opinions about changes in care based on the latest published scientific data. The use of these data to influence and change general clinical medical practice is well-established and remains the primary methodology accepted by most physicians; however, when these scientific data are applied at the practice level, they are often met with intense doubt, scrutiny, and mistrust.
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Prediction of coronary artery disease in patients with diabetes and albuminuriaWe developed a set of equations to predict the risk or probability of developing coronary artery disease (CAD) in 10 years among American Indians. The equations are based on the significant risk factors identified in the Strong Heart Study, a longitudinal study of cardiovascular disease in American Indians. The equations can be used in patient education and to evaluate the efficacy of CAD prevention and intervention programs.
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Never too old for statinsElderly patients with a history of an acute coronary syndrome (ACS) are at higher risk for subsequent cardiovascular events than younger patients.
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Noninvasive assessment of coronary artery bypass grafts with 64-slice computed tomographic angiographyWe evaluated the accuracy of the 64-slice computed tomography (CT) angiography scanner in subjects who were scheduled to undergo invasive angiography for possible stenosis in coronary artery bypass grafts. Results showed that the improved resolution of CT scanners with 64-slice technology allowed for a precise delineation of bypass graft occlusion or stenosis. It permitted an accurate noninvasive assessment of bypass grafts, even in subgroups of subjects with suboptimal scan conditions, such as those with arrhythmias or higher heart rates.
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New Framingham Heart Study global cardiovascular risk instruments: Helping physicians optimize their patients' cardiovascular careWhile most patients are concerned about their risk for myocardial infarction, it is important to remember that the risk factors for death from all cardiovascular diseases, including stroke, peripheral arterial disease, and coronary artery disease, are similar.
