Cardiology

An analysis of FIGARO-DKD from Kidney Week 2021 suggests finerenone use was associated with reductions in risk of multiple renal end points, including a 36% reduction in the need for dialysis.

Using the Steno Type 1 Risk Engine, a team from Denmark conducted a study suggesting SGLT2 inhibition could lower risk of cardiovascular disease and end-stage kidney disease in patients with type 1 diabetes.

An analysis of secondary end points from FIGARO-DKD presented at Kidney Week 2021 provides further insight into the effects of finerenone on kidney outcomes, including a 36% reduction in need for dialysis.

Results of the 5-year follow-up from SURTAVI, which were presented at TCT 2021, provide insight into the associations of TAVR with mortality and stroke compared to SAVR in patients with severe aortic stenosis considered to be at intermediate risk.

Data show reduction in systolic BP was considered greater than safety concerns related to drugs and interventional treatment, and preference for no intervention over intervention.

The adjusted change in 24-hour systolic blood pressure was -11.0 mm Hg in the chlorthalidone group and -0.5 mm Hg in the placebo group.

George Bakris, MD, takes part in a Q&A with Endocrinology Network staff to explore the design of the upcoming FIND-CKD trial and potential research priorities surrounding finerenone moving forward.

Data from the FAME 3 trial cast doubt on the role of FFR-guided PCI versus CABG among patients with 3-vessel coronary artery disease.

Data presented at ACR Convergence 2021 suggest statin initiation was associated with a 32% reduction in risk of cardiovascular disease, 54% reduction in risk of all-cause mortality, and a 33% increase in risk of type 2 diabetes.

In patients with advanced heart failure, the median NT-proBNP AUC for valsartan was 1.19 compared to an AUC of 1.08 for sacubitril/valsartan.

A time-conditional propensity score-matched analysis suggests statin initiation was associated with reductions in risk of cardiovascular disease and all-cause mortality but an increase in the risk of new diabetes in patients with rheumatoid arthritis.

Dr Gregg Fonarow explains how best to optimize the medical treatment of HFrEF.

Dr. Gregory Weiss describes gender disparities in cardiovascular care and what type of impact a comprehensive STEMI protocol could have on shrinking these gaps.

October's endocrine month in review features stories on the new ADA and EASD type 1 diabetes guidance, a phase 2 trial examining oral PTH tablets for osteoporosis, and a 3-part panel discussion focusing on diabetes management in 2021.

Chair of the guideline's writing committee Martha Gulati, MD, MS, offers perspective into the 10 take-home messages the guideline authors chose to highlight within the ACC/AHA 2021 chest pain guidelines.

The American College of Cardiology and American Heart Association guideline provides key highlights into the evaluation and diagnosis of adult patients with chest pain.

The latest cardiology case report from Brady Pregerson, MD, features a man in his late 50’s presents to the hospital for generalized weakness and SOB. Check out the EKG and determine the correct diagnosis.

Data show nonfatal MI did not meet the threshold for surrogacy for all-cause mortality or CV mortality.

This patient group had higher odds of death and longer lengths of hospital stays.

Data show women with AMI exhibited a more adverse cardiac risk factor profile and were more socially vulnerable than men in the US compared to Canada.

Our latest cardiology case report from Brady Pregerson, MD, features a man in his 60’s with body aches, subjective fevers, and loss of sense of taste for the past several days. Can you determine the correct diagnosis?

An analysis of data from multiple Danish registries provides evidence suggesting women who experience preterm delivery had 1.6-fold greater odds of developing hypertension later in life.

Data show In youth with obesity, but not healthy weight, visceral fat was positively associated with PWV and was predictive of PWV beyond BMI and waist circumference.

In 1774 estimated discharges where a hospital region in the US had been indicated, 35.9% were diagnosed in the West and 32.3% in the South.

Women who delivered preterm had a greater than 1.6-fold risk of hypertension and women who delivered extremely preterm had a 2.2-fold risk within the next 10 years.

In a Q&A, Guy Mintz, MD, provides perspective on the USPSTF draft recommendations surrounding aspirin for primary and secondary prevention, how the role of aspirin has evolved in recent decades, and how the news has caused a surge of questions in his practice.

Using data from SWAN DHS, investigators determined changes in menstrual cycle length prior to a woman's final menstrual period were associated with changes in carotid intima-media thickness and brachial-ankle pulse wave velocity.

An analysis of more than 9 million patients, including more than 5 million receiving both doses, provides insight into the risks of myocarditis associated with the BNT162b2 COVID-19 vaccine.

An analysis of more than 4 million singleton deliveries from more than 2.1 million women provides insight into the apparent increase in risk associated with preterm delivery.

Data show the overall risk difference between the first and second doses of BNT162b2 was 1.76 per 100,000 persons.