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September 11th 2024
The decision is based on rates of clinical and endoscopic remission with guselkumab in the ongoing phase 2b/3 QUASAR study.
An Increase in Infliximab Biosimilar Dose Escalation Results in Improved IBD Health Outcomes
There was a 0.9% increase in the first dispensation of infliximab, either the biosimilar or originator during the first year of follow-up, as well as a 16.2% increase in infliximab dose escalation, a 2.4% decrease in the dispensation of antibiotics, and a 2.6% decrease in the new use of prednisone.
Cyclosporine Bests Infliximab in Long-Term Efficacy for Acute Severe Ulcerative Colitis
The patients that did not undergo colectomy in the infliximab group were more often re-hospitalized because to the need for intravenous corticosteroids at the two-year follow-up compared to the cyclosporine group.
Investigators Identify Several New Predictors for Hepatitis B Vaccine Response in IBD Patients
Individuals that did not respond had a lower percentage of naïve T cells compared to responders, while responders had a lower percentage of Th2 and CD4 central memory subsets before vaccination.
Corticosteroid Use for IBD Associated With Increased Risk of Invasive Fungal Infections
The most common invasive fungal infection was histoplasmosis and the risk of invasive fungal infections was more than double in patients treated with corticosteroids than it was for patients treated with anti-TNFs.
Better Adherence Needed for Canadian Ulcerative Colitis Care Guidelines
The results show adherence to 6 quality indicators was linked to improvements in the post-intervention cohort with significant increases in C difficile testing, CRP testing, testing for latent tuberculosis, thromboprophylaxis, adequate corticosteroids prescription, and limitation of narcotics prescribed.