Neomi Shah, MD, MPH: The Need for Patient Sleep Assessment
Sleep apnea is associated with pulmonary, cardiovascular, psychiatric, neurologic, and weight-related effects. Primary care physicians need to monitor sleep health more.
Dr. Geoff Bellingan: The Future for Multi-Stem Cell Therapy
Previous analyses into MultiStem Cell Therapy have shown benefits and safety in stroke patients. What will it take for the therapy to reach a phase 3 trial for ARDS?
Stella Lee, MD: CRSwNP Patients, Before Dupilumab
Within a week of treatment on the investigative biologic, patients with severe form of the condition were reporting a return of smell and taste.
Using All the Pathways to PAH Care
Though the prostacyclin-targeting therapy selexipag is beneficial for PAH patients, investigators advise treatment to a trio of pathways.
High Regional Primary Care Use Associated with Less Critical Illness
Increased primary care use in a region was associated with reduced rates of ICU admission and mechanical ventilation use.
Providers Split on Family Presence During ICU Procedures
While 35% of providers say they’re unlikely to allow family to be present during ICU procedures, the 38% who say it’s a regular practice overwhelmingly call it a positive experience.
Neomi Shah, MD, MPH: Cardiovascular Risk Concerns in Sleep Apnea
Why are major adverse cardiovascular events not treated as the concern risk factors they are in patients with obstructive sleep apnea?
Reena Mehra, MD, MS: ADHERE Cohort Gender Findings
Upper airway stimulation, a sleep apnea treatment on the rise, is showing particular benefit for female patients.
Dr. Geoff Bellingan: MultiStem Cell Therapy in ARDS
Early-stage study results from the multi-center MUST-ARDS trial show the ex-vivo adult progenitor cell-expanding therapy is capable of improving 28-day mortality, care burden, and overall safety in patients with ARDS.
Thomas H. Goodin, PhD: The Burden of Depression on COPD
Mental health disorders are highly prevalent in certain patients with COPD—and their effect can limit lung function therapy benefit.
E-cigarettes May Leave Users Susceptible to Flu, Especially Women
Early research found that e-cigarette use affects the immune system response to the flu virus and the effects are different for female and male users.
Opioids in the ICU Not Linked to Continued Prescriptions
A multivariate cohort showed opioids in situation of critical care may not drive rates of continued use after 1 year.
Nintedanib Benefits FVC Decline in Systemic Sclerosis Plus ILD
The intracellular tyrosine kinases inhibitor has a similar benefit for patients with the rare, heterogenous associated form of ILD as it does for patients with IPF.
Dupilumab Improves Upper, Lower Airway Outcomes in SINUS Trials
Among patients in SINUS-24 and SINUS-52 with chronic rhinosinusitis with nasal polyps and comorbid asthma, dupilumab significantly improved function and patient-reported outcomes.
Donald Tashkin, MD: Advancing Marijuana Lung Health Trials
Does it matter whether federal and state regulations allow for a significant user population?
Selexipag Benefit Based on Time of Diagnosis
How new GRIPHON data showed further definitive long-term outcomes for patients with pulmonary hypertension.
Reena Mehra, MD, MS: The State of Sleep Apnea
Why are diagnoses still significantly underwhelming for a chronic condition on the rise?
COPD Risk Score May Help Guide Care Decisions
High-risk LIVE scores for patients with COPD were associated with higher all-cause mortality and higher rates of referral to palliative care.
Thomas H. Goodin, PhD: Understanding COPD Comorbidities & Gender Disparities
New Sunovion data at ATS 2019 shows expected trends of comorbidity effect on patients, and surprising results of care between men and women.
Budesonide-Formoterol Bests Albuterol in Asthma Exacerbation Prevention
In an open-label trial among adults with mild asthma, budesonide-formoterol treatment was superior to albuterol for the prevention of asthma exacerbations.
Mometasone, Tiotropium Show No Preferred Asthma Benefit in SIENA Trial
Investigators were seeking an alternative therapy for persistent asthma patients reporting insufficient benefit from mometasone, despite it being the guideline standard.
Ellipta Reports Significantly Better Inhaler Use to Device Combinations
The single-use triple-therapy device has proven significantly more easily managed by patients in a crossover study.
Mortality After Critical Illness Higher Among Seniors with Medicaid Insurance
Findings should prompt future investigations into care disparities at skilled-care facilities to mediate higher mortality rates observed among senior survivors of critical illness.
Cinnamon E-Cigarette Flavoring Linked to Impaired Lung Function
When inhaled, cinnamaldehyde can disrupt the lung's anti-bacterial defense system, exposing users to respiratory infection.
Awake Video-Assisted Thoracic Surgery Shown As Option for Patients with Poor Pulmonary Function
Of the 246 patients who underwent lung resections, 203 patients had a FEV1 less than 0.8.
Long-Term Pollution Exposure Linked to Elderly ARDS Hospitalizations
Increasing particulate matter and ozone rates, even in lower-pollution regions, is putting the elderly at risk of acute respiratory distress syndrome.
Budesonide/Formoterol Considered for As-Needed Asthma Therapy in Phase 3 Studies
The longtime therapy Symbicort was tested for safety and efficacy versus SABA in 8000-plus patients on an as-needed treatment basis.
Resurgence of Black Lung Disease in Coal Miners
Miners who have worked 10 or more years are at greater risk for developing black lung disease and progressive massive fibrosis.
Medicaid Expansion Associated with Decline in ICU Stays, Early Increase in Insurance Rates
Under Medicaid expansion, declines in ICU admission may mean that increased access to insurance has led to improvements in clinical outcomes.
Antibiotics Lengthen Hospitalization, Costs for Asthma Exacerbation Patients
The administration of the treatment to asthma patients is fairly common, despite guidelines advocating against it under certain circumstances.
