More Intensive Blood Pressure Goals Reserved for Most Severe Kidney Disease: KDIGO
November 17th 2014Recent updates by the 8th Joint National Committee (JNC 8), the American and International Societies of Hypertension (ASH-ISH), and KDIGO recommend target blood pressure of less than 140/90 mm Hg for most individuals, including those with CKD.
Updated Blood Pressure Guidelines from Major Bodies Agree on Targets in Kidney Disease
November 17th 2014Two major sets of hypertension guidelines released in 2014 contain more common threads than differences, and are intended to serve different purposes. Clinicians seeking guidance for managing hypertension in chronic kidney disease (CKD) can look for this common ground to avoid "guideline overload."
Hypertension Guidelines Still Leave Room for Clinical Judgment
November 17th 2014Guidelines for hypertension have converged on a blood pressure target of less than 140/90 mm Hg for most individuals with chronic kidney disease (CKD). However, studies still need to clarify optimal BPs for advanced disease and optimal cardiovascular prevention.
Making Improvements in Treating Kidney Disease
In the past there were few effective treatment options for serious conditions such as hepatitis C and lupus. However, recent scientific advances offer physicians and patients greatly improved options for effective management of these conditions, with fewer adverse events.
Pharmacogenetics Helps Fine-Tune Warfarin Dosing in Kidney Disease
November 16th 2014Though warfarin has long been the mainstay of anticoagulation in atrial fibrillation (AF), dosing is complicated by a host of factors, and the drug has a famously narrow therapeutic range. One way to fine-tune warfarin therapy is to account for genetic variation.
Consider Individual Risks, Benefits for Anticoagulation in Chronic Kidney Disease
November 15th 2014Anticoagulation is recommended for members of the general population with atrial fibrillation, but its significant risks must be weighed carefully in the medically fragile chronic kidney disease population.
Atrial Fibrillation Associated with Accelerated Renal Disease; Ablation May Help
November 15th 2014Treatment of atrial fibrillation (AF) in patients with CKD may help prevent disease progression. Ablation has been shown produce marked improvement in kidney function as measured by eGFR. A prospective study of individuals undergoing catheter ablation for AF showed that most patients remained AF-free, and that eGFR improved significantly for those with persistent or longstanding persistent AF.
Cinacalcet May Reduce Cardiovascular Risk for Older Kidney Disease Patients: EVOLVE Re-Analysis
November 14th 2014Secondary hyperparathyroidism can occur in CKD when the kidney loses its ability to produce active metabolites of vitamin D, and reduces phosphorus excretion. Cinacalcet seeks to interrupt the progression to severe unremitting hyperparathyroidism by mimicking calcium to the calcium-sensing receptors that control parathyroid hormone levels.
Understanding ANCA-Associated Vasculitis
Affecting just one in every 100,000 people, ANCA-associated vasculitis is not one of the more common conditions nephrologists will encounter. However, without proper treatment it can have serious adverse effects on a patient's life.
Maintaining Blood Pressure Remains a Challenge During Dialysis
For patients on dialysis one of the biggest concerns is whether their blood pressure will stay at a healthy level during the process. While there have been some advances made more work needs to be done to help patients in need.
Cardiac Regeneration Provides Hope for Future Heart Patients
Heart failure and other cardiac events can leave lasting effects on the lives of patients. Scientists are working on ways to help make the recovery process easier and smoother by generating cells that can help the healing process.
Obesity No Longer a Hindrance for Kidney Donation
In the past patients diagnosed as obese would be automatically disqualified from receiving a kidney transplant. Now, thanks to advances in robotic surgery there are new options that can help give these patients a new lease on life.
Kidney Care Matters From Birth
From the very earliest age a person's kidneys play a pivotal role in their overall health. This can be especially true for premature babies and others who have suffered early kidney injuries. The treatment they receive can go a long way in helping them with the rest of their lives.
Why Nephrologists Exclude Patients from Referral for Kidney Transplant: A Survey
November 10th 2013A recent anonymous survey among nephrologists suggests that patients' social support, ability to understand the transplant process, and age are the most important factors influencing nephrologists' decisions to exclude them from kidney transplant referral.
In Hemodialysis Patients, Renin-Angiotensin System Inhibitors Reduce All-Cause Mortality Risk
November 9th 2013A recent study found that drug regimens containing renin-angiotensin system (RAS) inhibitors are associated with a lower risk of cardiovascular and all-cause deaths among patients starting hemodialysis, compared to regimens containing only beta blockers (BBs).
Mobile App Informs Decisions on Kidney Transplant, Dialysis
November 8th 2013After developing a predictive model that compares a patient's individualized risk of mortality while undergoing dialysis to the risk of kidney transplant, a research team has created a free mobile app called iChoose Kidney that enables patients and providers to make informed decisions on treatment choices.
Acute Kidney Failure Is More Prevalent Among African-Americans
November 8th 2013Results of a recent community-based study suggest that African-American patients are at higher risk for acute kidney injury (AKI) than Caucasians - a difference that appears to be related to disparities in income and socioeconomic status.
Vascular Calcification Shown on X-Ray Assesses Cardiovascular Risks in Chronic Kidney Disease
November 8th 2013A recent study presented at Kidney Week 2013 suggests that a plain X-ray is a reliable and inexpensive tool for assessing the risks of cardiovascular events and death in patients who have chronic kidney disease (CKD) and are not on dialysis.