Article
Do You Speak DPP-4I?
There are 10 FDA-approved DPP-4 inhibitors--single agents and combination products. Do you speak their language? Find out with these 5 questions.
Dipeptidyl peptidase-4 inhibitors (DPP-4Is) have been in the type 2 diabetes tool box since 2006. They are associated with a modest decrease in A1c and a mostly neutral impact on weight. There are currently four approved agents in the US and there are also five approved agents that combine a DPP-4I with metformin and one that combines a DPP-4I and a thiazolidinedione.
How well versed are you in the language of DPP-4I? Find out in 5 short questions.
1. Which one of the following DPP-4I combination drugs does NOT contain metformin:
A. Tradjenta
B. Kombiglyze
C. Kazano
D. Jentadueto
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Answer: A. Tradjenta
Tradjenta is the DPP-4I linagliptin
2. The DPP-4I combination drug that contains a thiazolidinedione is:
A. Nesina
B. Trulicity
C. Oseni
D. Onglyza
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Answer: C. Oseni
Oseni combines alogliptin and pioglitazone; Nesina is alogliptin; Trulicity is dulaglutide; Onglyza is saxagliptin
3.Kazano combines metformin with which of the following DPP-4Is?
A. Linagliptin
B. Sitagliptin
C. Saxagliptin
D. Alogliptin
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Answer D. Alogliptin
4. Januvia is the brand name for which of the following generic DPP-4Is?
A. Alogliptin
B. Linagliptin
C. Sitagliptin
D. Saxagliptin
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Answer: D. Sitagliptin
5. Jentadueto is the brand name for the combination of saxagliptin and metformin.
A. True
B. False
Please click here for answer and table of all drugs mentioned
Anwer: B. False
Jentadueto is linagliptin and metformin
Table. DPP-4Is, DPP-4I Combinations, GLP-1 Receptor Agonists
Generic
Brand
Generic
Brand
Sitagliptin
Januvia
Saxagliptin/metformin
Kombiglyze
Saxagliptin
Onglyza
Alogliptin/metformin
Kazano
Linagliptin
Tradjenta
Alogliptin/pioglitazone
Oseni
Alogliptin
Nesina
Exenatide (GLP-1)
Byetta
Sitagliptin/metformin
Janumet/Janumet XR
Exanatide (GLP-1)
Bydureon
Linagliptin/metformin
Jentadueto
Dulaglutide (GLP-1)
Trulicity
