News

Moxetumomab pasudotox (Lumoxiti, AstraZeneca)is approved for adults with relapsed or refractory HCL who received at least 2 prior systemic therapies, including treatment with a purine nucleoside analog.

A subcutaneous formulation of tocilizumab (Actemra) is now approved for the treatment of active systemic juvenile idiopathic arthritis in patients at least 2 years old.

The FDA has approved the subcutaneous formulation of tocilizumab (Actemra) for the treatment of active systemic juvenile idiopathic arthritis in patients two years of age and older.

Novartis reported that 59% of patients at 24 weeks experienced little to no impact of their condition on their quality of life. Additionally, 87% of bio-naïve psoriasis patients remained on secukinumab through 12 months, indicating its tolerability in real-world settings.

The FDA has granted an orphan drug designation to Syntimmune Inc.’s SYNT001 for the treatment of pemphigus.

At 12 weeks, patients with rheumatoid arthritis receiving filgotinib responded and achieved low disease activity at significantly higher rates compared to placebo.

The acceptance comes less than a month since the FDA had approved the anti-VEGF therapy for the treatment of wet AMD. Its mechanism of action allows it to block new blood vessel growth and the passing of fluids through blood vessels in the eye.

A new meta-analysis aimed to quantify the effect, if any, of physician burnout on patient wellbeing. They found the links are strong and consequential.

Data presented at the2018 World Congress on Parkinson's Disease and Related Disorders indicate that valbenazine is a promising treatment for tardive dyskinesia, while opicapone may be a new effective treatment for Parkinson disease.

The FDA has granted a fast track designation to pamrevlumab for the treatment of patients with idiopathic pulmonary fibrosis (IPF).

The supplemental BLA seeks FDA approval for alirocumab (Praulent) as a treatment to reduce overall risk of major adverse cardiovascular events.

An investigative team from St. Jude Children’s Research Hospital have identified weaknesses to target in rhabdomyosarcoma, leading to a promising precision medicine treatment that has already hit clinical trials.

After 10 days of transcranial magnetic stimulation, patients reported significant decreases in withdrawal symptoms like craving, quality of sleep, and mood status.

The combination of montelukast and budesonide was found more effective than budesonide alone in children with chronic cough-variant asthma in a China retrospective study.

A study of primary care patients found that of patients screened for alcohol use, just 2.4% were also screened for depression. Men and racial/ethnic minorities were less likely to be screened for depression.

A daily dose of aspirin could reduce HIV transmission rates by reducing inflammation and thus the number of HIV target cells in the female genital tract.

The FDA has granted a fast track designation to Immune Pharmaceuticals, Inc.’s bertilimumab for the treatment of bullous pemphigoid.

New research says it’s medically possible to use HCV-positive patients as liver donors. Now, a new study finds it’s also cost-effective.

Many first responders were exposed to particulate matter that led to their development of World Trade Center Lung Injury, a collection of chronic respiratory conditions, such as asthma and emphysema.

Interestingly, increased distress led to a higher risk of stroke for women, while distressed men had a higher risk of heart attack.

A whitepaper presents practical, expert opinion-based recommendations for preventing and testing for C difficile infection in the NICU.

The FDA has denied accelerated approval for Pompe disease treatment, AT-GAA. However, plans for a pivotal study are still underway, so approval could be forthcoming.

Investigators find telavancin has potent in vitro activity and low resistance development potential when used against S aureus isolates in patients with cystic fibrosis.

There’s no cure for Huntington’s disease, but a new study by investigators in Sweden is exploring potential new approaches to treating the neurodegenerative disease.

Flexible, individualized counseling for HIV patients who also use injection drugs also resulted in improved viral suppression.

Investigators found that asthma symptom severity results from the interaction of genetic susceptibility to pollution together with the severity of pollution exposure.

Mice treated with ACE inhibitors demonstrated preservation of cognitive function, preserved dendritic complexity, a normal spine number, and significantly less microglial activation.

High Impact Chronic Pain encompasses individuals with chronic pain who also have a disability. Data collected in this study will help improve care for patients with HICP and guide future research.

The risk of acute coronary syndrome recurring after hospitalization was not found to be increased in individuals infected with HIV.

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