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The findings support exploration of LAC as a biomarker and therapeutic target that might help guide individualized treatments in the spirit of precision medicine.

A post-hoc analysis of data from the TREX-AMD trial has determined that eyes with neovascular age-related macular degeneration and treated with ranibizumab, develop more macular atrophy lesions within baseline choroidal neovascularization regions than outside those regions.

A review of the research on eHealth and mHealth interventions for youth with HIV concludes these types of interventions should be scaled up and more widely implemented.

The 30-person panel, including physicians and patients, recommended a median 12.5 tablets of 5mg opioid for 20 common procedures.

This combination of telmisartan, amlodipine, and chlorthalidone reduced blood pressure to target levels in 69.5% of patients at 6 months, compared to 55.3% of patients receiving usual care.

The first patients have been treated in a phase 2 trial evaluating ALLN-177 in adults and adolescents with primary hyperoxaluria or enteric hyperoxaluria with advanced chronic kidney disease (CKD) and elevated plasma oxalate.

The FDA has granted an orphan drug designation in a second indication to Martin Pharmaceuticals’ trimetazidine dihydrocholoride (LIVANTRA) for the treatment of pulmonary arterial hypertension (PAH).

A Denmark retrospective study of 7 million-plus individuals found associations between increased TBI severity and frequency, and suicide risk.

Investigators from Cincinnati Children’s find that statins can effectively treat pulmonary alveolar proteinosis, a rare autoimmune disease.

Investigators find more evidence to support IgE as a reliable biomarker for targeted biologic therapy in asthma management.

The FDA has granted an orphan drug designation to Onspira Therapeutics’ OSP-101, the first and only inhaled interleukin-1 receptor antagonist (IL-1Ra) for the treatment of bronchiolitis obliterans.

Chervenak was recently appointed chair of the department of obstetrics and gynecology at Lenox Hill Hospital and chair of the academic department of obstetrics & gynecology and associate dean for international medicine at the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell.

The recall comes after the FDA issued an Import Alert concerning Sichuan Friendly Pharmaceutical Co., Ltd., which was found to have substandard manufacturing practices.

In its phase 2 trial, acebilustat (CTX-4430) was found to show clinically meaningful improvement in pulmonary exacerbations in patients with cystic fibrosis.

: In a recent phase 3 SONICS study, levoketoconazole was found to be well tolerated in patients with endogenous Cushing’s syndrome.

Participants in the Project LifeSkills intervention had a 39.8% greater mean reduction in condomless sex compared to participants receiving standard care.

The FDA has granted a rare pediatric disease designation to CLR 131 for the treatment of Ewing’s sarcoma.

The device is used in conjunction with cataract surgery for patients with mild to moderate primary open-angle glaucoma.

If approved in early 2019, the nasal spray would become the first approved therapy indicated for seizure clusters in 17 years.

The FDA has granted an orphan drug designation to MeiraGTx Holdings Plc’s AAV-CNGA3 for the treatment of achromatopsia caused by mutations in the CNGA3 gene.

New research outlines the role of neutrophil cytoplasts in severe asthma which could lead to new therapeutic pathways to treat the disease.

The designation was based on data from 7 clinical trials over the past decade which assessed Xolair's efficacy and safety versus various food allergens such as peanut, milk, and egg.

These mistakes can be as simple as a worker touching their face before removing contaminated gloves.

A small number of cases of neural tube defects in babies born to mothers who were taking dolutegravir at the time of conception are prompting expanded study of the use of the drug in pregnant women.

Troy Trygstad spoke with MD Magazine® about the upcoming flu season and emphasized how different clinicians and parts of the healthcare system can play a role in promoting immunization.

Stay up-to-date on the latest rare disease news by reading the top 5 articles of the week.

Over time, it has become evident that suicide involves a complex mix of genetics, temperament, circumstances, external support, and access to means.

Galafold differs from common enzyme replacement therapy in that it increases the activity of the body’s deficient enzyme.

The FDA has approved migalastat (Galafold), the first oral medication for the treatment of adults with Fabry disease.

The Annovera combines segesterone acetate and ethinyl estradiol to prevent pregnancy and has a 2-4% failure rate.