News

Chicago-based pain specialist Scott Glaser, MD, is on a crusade. He wants his colleagues to stop using an injection technique that paralyzed his own patient.

Successful preliminary trials revealed that treatment with a novel anti–interleukin-23 monoclonal antibody, guselkumab, (CNTO 1959/Janssen) was more effective at reducing the symptoms of plaque psoriasis than adalimumab.

Opioid analgesics are often prescribed to patients who suffer from chronic lower back pain; however, a new report suggests that these medications are less effective in a subset of these patients.

Inflammatory chronic diseases such as rheumatoid arthritis, ankylosing spondylitis, and psoriasis bring many treatment challenges. Among them is the fact that biologic therapies for these diseases-particularly anti-TNF agents-while effective, can themselves bring reactivation of a latent tuberculosis infection.

Low back pain is notoriously difficult to treat in common patients. For pregnant patients, who experience low back pain at significantly higher rates, pain management specialists can face some additional and unique challenges.

Study results indicate that low-field magnetic stimulation synchronized to an individual's alpha frequency-dubbed "synchronized transcranial magnetic stimulation"-appears to be safe, effective, and well tolerated for treating major depressive disorder when properly administered.

Study results suggest that brain inflammation resulting from chronic nerve pain appears to alter activity in brain regions that regulate mood and motivation. The findings indicate, for the first time, a direct biophysical relationship between long-term pain and the co-morbid anxiety, depression, and substance abuse observed in more than 50% of patients with chronic nerve pain.

More than 50% of patients infected with the Ebola virus during the recent outbreak passed away as a result of the disease, according to a panel of independent experts that assessed the World Health Organization's (WHO) response to the Ebola crisis that began in West Africa in 2013.

Not only have researchers uncovered a key factor that drives neuropathic pain, they have also identified a strategy to reverse it.

Cardiac disease could be a predictive factor for Alzheimer's disease and dementia, according to research published in Circulation.

Pain and itching may be controlled by cells on the spinal cord, according to research published in Neuron.

A review of research on the use of testosterone replacement therapy in men with a history of prostate cancer and in men with elevated prostate cancer risk found no evidence of statistically significant associations between such treatment and cancer progression.

A multi-year study of rivaroxaban in patients with non-valvular atrial fibrillation demonstrated that the drug is about as safe in real-world usage as it was in phase 3 trials.

There are difficult patients, and ideal patients. A cardiologist offers advice on relating to them all.

Study results show treatment with certolizumab pegol and methotrexate produced significant symptom improvement in patients with rheumatoid arthritis.

A recent study looked at the effect from injections of recombinant human growth hormone (HGH) and testosterone to the painful and dysfunctional areas in patients with chronic lower back pain.

Patients with psoriasis and psoriatic arthritis (PsA) commonly experience joint pain. They are also at higher risk for cardiovascular disease (CVD).

New research may help explain the connection between exocrine pancreatic insufficiency, gastric bypass surgery, and oxalate nephropathy in humans.

With 5 grants totaling nearly $4 million, researchers will target deadly infectious diseases transmitted to humans via mosquitos.

The US Food and Drug Administration announced the approval of Entresto for the treatment of heart failure.

Researchers announced a phase 3 trial assessing secukinumab for the treatment of psoriatic arthritis met its primary endpoint (ACR 20 at week 24), possibly putting the drug on the fast track to approval.

Researchers have found a genetic cause for the increased coronary artery disease risk experienced by some patients with migraine; however, this relationship may be limited to those who suffer from a specific kind of migraine.

The toxins in the venom of a particular species of cone snail may hold the key to developing more effective pain treatments.

Gilead Sciences recently announced that Japanese regulators have approved its single-tablet combination drug Harvoni (ledipasvir 90 mg/sofosbuvir 400 mg) for the treatment of hepatitis C infection genotype 1 in adults.

The benefits of weight loss for patients undergoing gastric bypass surgery have been well established, but now researchers are focusing their attention on the procedure's benefits for patients with type 2 diabetes mellitus.

As the summer grilling season swings into high gear, the Centers for Disease Control and Prevention (CDC) has issued a warning regarding the health risks from accidentally ingesting wire bristles from the brushes commonly used to clean BBQ grills.

As fecal microbiota transplantation (FMT) has gained acceptance and popularity as a treatment for c. difficile infection, researchers have also been investigating the benefits of the procedure for treating other disorders of the gut, including ulcerative colitis (UC).

Endocrine regulation in ejaculation control is still not well understood. Sex steroids (testosterone and estradiol), pituitary (prolactin and oxytocin), and thyroid hormones may regulate the ejaculatory process, but exact mechanisms are unclear.

Not only has "the world's most sensitive test to detect and diagnose infectious disease" been developed, but it has the potential to become a doctor's office staple.

A low body mass index may present an accelerated risk for premature death in rheumatoid arthritis patients, according to research published in Arthritis & Rheumatology.