News

Early reports from the Safety and Appropriateness of Growth hormone treatments in Europe (SAGhE) project noted increased cardiac and cerebrovascular mortality in adults who were treated for stature problems as children. In addition, other studies have linked stroke risk to short stature in general, hypothesizing that shorter people have increased metabolic risks.

Endocrinologists generally see middle-aged people who have developed type 2 diabetes mellitus (T2DM) subsequent to overnutrition (or overeating) and weight gain. Most clinicians tend to forget that low caloric intake, or undernutrition, in the prenatal period or during a child's formative years also seems to increase the risk of the T2DM later in life.

Why do some allergic reactions produce only relatively mild symptoms while others trigger anaphylaxis and eventual death?

Obesity in children is a very complex problem. How children eat and what they believe about food and obesity is largely determined in their family units.

Kidney donors may have lower 1,25-dihydroxyvitamin D and phosphate levels. Their parathyroid hormone levels may be elevated, but with minimal effect on calcium levels.

Patients with advanced colorectal cancer previously only had access to limited treatment options; however, new research presented at the 26th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Barcelona, Spain, indicated a combination of 3 targeted drugs could potentially serve as a successful treatment.

In the first test of an Ebola virus vaccine in the US, the University of Maryland announced it will soon start human trial.

The maker of Sovriad (simeprevir) has revised the drug's package insert labeling on the order of Japanese health officials following the deaths of three people who took the hepatitis C drug.

Patients with cirrhosis who took part in a study that tested a triple combination drug for hepatitis C with ribavirin saw normalization of key laboratory tests after three and six month treatment periods, an indication of improved liver condition.

Study results show good outcomes for hip replacement in patients under age 35 diagnosed with juvenile idiopathic arthritis who have failed to respond to previous treatment.

Study results show that patients diagnosed with rheumatoid arthritis and who are either significantly underweight or overweight/obese have lower sustained remission rates compared with their normal weight counterparts.

Hysingla ER (hydrocodone bitartrate) is a single-entity oral hydrocodone tablet that is administered to treat pain severe enough to require daily, around-the-clock, long-term opioid treatment and for which alternative treatment options are inadequate.

Clinicians who see their own clinical outcomes data (sometimes referred to as surgeon-specific mortality data) can use that information to promote and enhance patient safety. However, critics of this approach argue that places the burden solely on the surgeon and under-appreciates the surgical team's role and dismisses hospital staffing, infrastructure, and process as contributors to patient safety.

When surgical patients have tumors that secrete adrenal hormonal, the anesthesiologist needs to thoroughly address preoperative evaluation, perioperative hemodynamic control, electrolytes, and metabolic abnormalities

Almost everyone has episodes of low back pain (LBP) from time to time. Fortunately, most episodes of LBP are considered acute, and resolve within 6 to 12 weeks. When LBP pain persists and becomes chronic, treatment is considerably more complicated and often leads the patient to the surgical suite.

Guidelines from the Endocrine Society report that postmenopausal women with hypoactive sexual desire disorder may benefit from up to 6 months of testosterone replacement therapy but recommend against its use in otherwise healthy women.

The symptoms of depression were reduced in mice models which had high levels of PGC-1a1 in their skeletal muscle.

Monitoring injured workers by testing urine samples can increase prescription consistencies, according to a recent study.

Researchers have found that maintenance treatment with methadone or buprenorphine may help prevent hepatitis C infection among injection drug users, a population with the highest risk of infection of the virus.

Analysis of insurance claims and medical records indicates that people with mitral annular calcification may face a greatly elevated risk of incident atrial fibrillation.

A doctor who contracted the Ebola virus in Africa and was brought to a Nebraska medical center over the weekend for treatment has died, officials said Monday.

Thyroid dysfunction causes many well-recognized changes at the level of the brain, and most are reversible with treatment. Patients who have hypothyroidism often have other neuropsychiatric comorbidities, including affective disorders, depression, cognitive function loss, anxiety, or irritability.

Among diabetics, poor adherence or nonadherence results in poorer glycemic control and increased risk of complications and disability, as well as increased healthcare costs.

New evidence indicates that mitochondria are a crucial element in metabolic homeostasis in white adipocytes. They appear to have significant involvement in adipogenesis, fatty acid synthesis and esterification, branched-chain amino acid catabolism, and lipolysis

Genzyme announced the FDA has approved Lemtrada (alemtuzumab) for the treatment of patients with relapsing forms of multiple sclerosis.

The launch of MS Radio aims to spread information, host discussions, and present features for multiple sclerosis patients, caregivers, and clinicians.

Nebraska Medical Center's biocontainment unit is preparing for a new patient. Martin Salia, 44, a surgeon who is completing a residency in Freetown, Sierra Leone, but resides in New Carrollton, MD, is apparently the sixth doctor in Sierra Leone to be infected with the Ebola virus. He was doing the residency at Kissy United Methodist Hospital, a general hospital, not an Ebola center. Meanwhile, new Ebola vaccines are headed for trials.

About half of all adults afflicted with obstructive airway disease have symptoms overlapping with chronic obstructive pulmonary disease (COPD) and asthma. According to data presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting, this makes the possibility of misdiagnosis and mistreatment more likely.

A hepatitis C vaccine manufactured by researchers from Oxford University has shown promising potential in an early clinical trial.

Multiple sclerosis is almost conclusively an immune system disease, not a nervous system disease, according to a study published in Nature.