Prepared by Deepak Kumar, MD, Joshua E. Lane, MD, and David E. Kent, MD, Department of Medicine, Mercer University School of Medicine, Macon, Ga

An otherwise healthy 28-year-old man has had easily stretchable skin and hypermobile joints since early childhood. He did not bruise easily and had no family history of similar abnormalities. Physical examination showed extreme distensibility of his skin (Figure 1) and striking hypermobility of many joints, especially evident in the hands (Figure 2).

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