Opinion
Video
Author(s):
Retina specialists evaluate the effectiveness of the two new therapies for neovascular AMD and DME by analyzing their respective clinical trial methodologies and outcomes.
0:00 Introduction
1:05 Overview of faricimab and high-dose aflibercept
3:48 clinical trials for faricimab and high-dose aflibercept
9:12 Comparing the matched dose phase results in clinical trials
12:30 Potential impacts of Ang-2 inhibition
14:40 Real-world experience with faricimab
22:00 Challenges with step therapy
24:00 Choosing between faricimab vs high-dose aflibercept
29:00 Perspectives on retreatment criteria in clinical trials
33:00 Label differences between faricimab and high-dose aflibercept
35:00 Final remarks