Implementation and Use of Patient-Reported Outcomes in Heart Failure with Stephen Greene, MD

Hear from Stephen Greene, MD, as he takes a deeper dive into a recent study he led comparing use of NYHA class vs. KCCQ-OS to capture changes in disease state among patients with heart failure with reduced ejection fraction.

Episode Highlights

1:20 - Key Takeaways from Study

3:30 - Role of PROs in the Future

6:50 - Barriers to Incorporating PROs in Practice

8:30 - What prognostic value do PROs add

10:20 - Limitations within the analysis

12:57 - Plans for further study

In this episode, Stephen Greene, MD, of the Duke Clinical Research Institute, breaks down a recent study he led comparing the sensitivity of NYHA class versus patient-reported outcomes for capturing changes in disease state among patients with heart failure with reduced ejection fraction.

Briefly, the study used data from the CHAMP-HF registry to identify a cohort of more than 2k HFrEF patients and found PRO, as measured by the Kansas City Cardiomyopathy Questionnaire overall summary score (KCCQ-OS), was more sensitive and better at tracking meaningful changes in health status over time when compared to use of NYHA class.

For more on use of KCCQ-OS vs. NYHA class, check out our coverage of Greene's study.