Patient Case No. 2

Author(s):

Manesh R. Patel, MD,Payal Kohli, MD, FACC

Key Takeaways

Difficult-to-treat hypertension involves uncontrolled blood pressure despite using three or more antihypertensive medications, including a diuretic.
It is distinct from resistant hypertension, which is more common and may not include a diuretic in treatment.
This condition affects a smaller subset of patients with high blood pressure and requires a comprehensive management approach.
Lifestyle modifications and evaluation for secondary causes are crucial for optimal management of difficult-to-treat hypertension.

Panelists discuss how chronic kidney disease (CKD) and uncontrolled hypertension create a damaging cycle, in which hypertension accelerates kidney damage while declining kidney function makes blood pressure harder to control.

EP: 1.Unmet Needs in HTN: Patient Adherence, Comorbid Conditions, and Prevalence

EP: 2.Current Limitations With Traditional Antihypertensive Drugs

EP: 3.Drug Classes Available to Treat Patients With High Blood Pressure

EP: 4.Difficult-to-Treat Hypertension Treatment Strategies

EP: 5.Current Therapeutic Guidelines for Managing Resistant Hypertension

EP: 6.Endothelin Pathway

EP: 7.PRECISION trial

EP: 8.Hypertension in Pregnancy and Women

EP: 9.Tips for Precise Readings

EP: 10.Patient Case No. 1

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EP: 11.Patient Case No. 2

Patient No. 2 has stage 3 CKD and uncontrolled hypertension. They have a moderate reduction in their estimated glomerular filtration rate, confirming stage 3 CKD. Their hypertension is likely contributing to CKD progression.