Role of Testing in CSU Diagnosis

Author(s):

Key Takeaways

Routine blood tests, such as ESR, CRP, IgG anti-TPO, and total IgE, are recommended for diagnosis.
Biopsy is generally not required for diagnostic testing in this context.
Disease severity is assessed using UAS7 and UCT, evaluating symptom frequency, intensity, and control.

Panelists discuss the recommended diagnostic testing for chronic spontaneous urticaria (CSU), noting that extensive testing is not necessary and that routine blood counts, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), IgG anti-thyroid peroxidase (TPO), and total IgE are adequate, while also addressing the limited role of biopsy; they further explore how disease severity is assessed using tools like Urticaria Activity Score (UAS7) and Urticaria Control Test (UCT).

EP: 1.Overview of CSU: Prevalence and Presentations

EP: 2.Impact of CSU on Patient Quality of Life

EP: 3.Pathophysiology of CSU and Role of BTK

EP: 4.Diagnostic Approach to CSU

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EP: 5.Role of Testing in CSU Diagnosis

EP: 6.Referring CSU Patients to a Specialist

Video content above is prompted by the following:

Is testing recommended for diagnosis, and if so, which kind?
- Extensive testing not needed: routine blood count. ESR and/or CRP, and IgG anti-TPO and total IgE (according to guidelines)
- What is the role, if any, of biopsy in diagnostic testing?
How is disease severity assessed?
- UAS7
- UCT