Smoking Linked to Higher Risk of Death among Colorectal Cancer Survivors
February 4th 2015Colorectal cancer survivors who smoke cigarettes were found to face more than twice the risk of death than non-smoking survivors, corroborating existing evidence that cigarette smoking is associated with colorectal cancer-specific mortality.
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Clinicians Encouraged To Discuss Sexual Function with IBD Patients
February 2nd 2015While many women (and men) with inflammatory bowel disease (IBD) have experienced some level of sexual dysfunction, according to recent data, only less than one in 10 female patients revealed their physicians speak with them about this issue.
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New Minimally Invasive Test IDs Patients for Barrett's Esophagus Screening
February 2nd 2015A new minimally invasive cell sampling device, Cytosponge-TFF3, coupled with assessment of trefoil factor 3 expressions, can successfully identify patients with reflux symptoms who warrant endoscopy to diagnose Barrett's esophagus.
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FDA Approves HIV-1 Infection Treatment
January 29th 2015Bristol-Myers Squibb announced today the US Food and Drug Administration (FDA) has granted approval for Evotaz tablets in combination with other antiretroviral agents for an innovative treatment option for adults suffering from HIV-1 infection – delivering proven suppression through 48 weeks.
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Human Pluripotent Stem Cells: The Future of Hair Regeneration?
January 29th 2015Hair loss, whether partial or close to baldness, is a condition that is frequently associated with feelings of poor self-confidence (even depression in severe cases) across all demographics of affected patients.
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Steroid Therapy: Increasing Risk of Blood Clots 5-fold in IBD Patients
January 29th 2015Corticosteroid (steroid) is associated with an approximately 5-fold increase of venous thromboembolism in patients suffering from inflammatory bowel disease (IBD), according to a new study published in Clinical Gastroenterology and Hepatology.
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Hepatitis C: What Therapy this Week?
January 24th 2015"We really have entered this new era of direct acting antivirals, and as of this fall, we've finally laid to rest interferon in the grave that we've all been wanting to put it in, for more than 2 decades," said Jacqueline G. O'Leary, MD, MPH, during her presentation at the 2015 AGA Clinical Congress of Gastroenterology & Hepatology.
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Meeting the Challenges of Value Demonstration in GI Practice
January 23rd 2015"There are only 2 or 3 things I know for sure. Only 2 or 3 things. That's right. Of course, it's never the same things, and I'm never as sure as I'd like to be," nuggets of wisdom (from the novel "Bastard Out of Carolina," by Dorothy Allison) that Thomas Murray, Senior Director of Quality Measurement & Improvement, AGA, shared at the 2015 AGA Clinical Congress of Gastroenterology & Hepatology.
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Transoral Fundoplication: Effective GERD Treatment?
January 21st 2015According to a new study published in Gastroenterology, research results showed that transoral fundoplication, an incision-less procedure allowing anti-reflux valve alteration, is an effective treatment for patients afflicted with gastroesophageal reflux disease (GERD).
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Research Offers New Insight into Hirschsprung's Disease
January 16th 2015Researchers discovered defects in the Sox10 protein, a factor regulating gene expression, which evidently plays a role in developing post-operative gastrointestinal (GI) function in patients afflicted with Hirschsprung's disease.
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Interferon-free Combination Therapy Can Prevent Post-transplant HCV Recurrence
January 12th 2015Following 2 recent studies published in Gastroenterology, researchers reported that a 24-week course of sofosbuvir and ribavirin could eliminate hepatitis C virus (HCV) infection in two-thirds of patients who undergo liver transplantation.
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FDA Approves New Enteral Treatment for Parkinson's Disease
January 12th 2015DUOPA (carbidopa and levodopa) enteral suspension for the treatment of motor fluctuations for people with advanced Parkinson's disease is administered via portable infusion pump that delivers carbidopa and levodopa directly into the small intestine for 16 continuous hours.
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Review: Use of SSRI Increases Upper GI Bleeding Risk
January 7th 2015According to a recently published analysis in the January issue of Clinical Gastroenterology and Hepatology, treatment with selective serotonin reuptake inhibitor (SSRI) is connected with increased risk of upper gastrointestinal bleeding (UGIB).
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Link between Pigment Production and Mitochondrial Function in Melanoma
January 5th 2015New research published in the January 2015 issue of FASEB Journal highlighted a direct correlation between mitochondrial function alterations and the production of melanin in cancerous skin cells. Researchers found that as melanoma cells produce increased melanin pigment, the mitochondria retaliates by matching production levels of reactive oxygen species.
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Cholera Bacterium: Silent Murderers?
January 5th 2015A group of scientists have recently discovered the method to cholera bacterium's madness: horizontal gene transfer‑stabbing and killing other bacteria to absorb their DNA. The disease, which is associated with acute watery diarrhea, is often caused by Vibrio cholera (V. cholerae) infection within the small intestine.
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Inherited Gut Bacteria Drives Crohn's Disease and Ulcerative Colitis
December 18th 2014A team of researchers recently reported that human genes may partially influence intestinal bacteria spurring inflammatory bowel disease (IBD) conditions like Crohn's disease (CD) and ulcerative colitis (UC).
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