Andrew Smith

At least 5 studies indicating that testosterone replacement therapy either has no effect on cardiovascular health -- or tends to improve it -- appeared during the 3-week period immediately after the US Food and Drug Administration's controversial decision to mandate warnings about the potential cardiovascular risks of such treatment.

Results from a long-term trial indicate that sublingual immunotherapy, though quite safe, is rarely fully effective in people with severe peanut allergies.

Researchers have long known that single men tend to have more testosterone than comparable men in long-term relationships, but what about men in new relationships? A new study finds that testosterone generally remains at "single-man" levels until couples have been dating for more than a year.

New research suggests that the relative ease of using novel oral anticoagulants may be spurring more patients with atrial fibrillation to try anticoagulation and stick with it.

Analysis of a population-based cohort indicates that patients with psoriasis and psoriatic arthritis face an elevated risk of developing heart arrhythmias such as atrial fibrillation.

A new investigation of the molecular and cellular mechanisms that produce diabetes may explain the strong association between cystic fibrosis and pancreatic complications.

The increasing prevalence of food allergies (along with increasing awareness of the dangers associated with those allergies) has famously led to food restrictions in schools and on commercial airlines. The trend has now spread to a venue that's strongly associated with the enjoyment of fresh roasted peanuts: baseball stadiums.

The US Food and Drug Administration has warned physicians that it may be dangerous to use a device known as the Lariat to close the left atrial appendage in patients with heart arrhythmias.

A review and meta-analysis of a dozen studies indicates that more than 10% of all psoriasis patients have undiagnosed cases of psoriatic arthritis.

New research into vitamin K deficiency among cystic fibrosis patients may help explain why exocrine pancreatic insufficiency increases the risk of pathological shortages.

Treatment with anti-TNF drugs and DMARDs is associated with clinically significant improvement measures of work disability such as presenteeism and productivity loss in patients with psoriatic arthritis.

Study shows that diabetes duration (ie, how long they've had the disease) is linked with an increased risk of thromboembolism in patients with atrial fibrillation, but not with an increased risk of anticoagulation-related bleeding.

Research using mouse models may offer clues to potential prophylactic approaches for patients with venom sensitivity.

A review of research on the use of testosterone replacement therapy in men with a history of prostate cancer and in men with elevated prostate cancer risk found no evidence of statistically significant associations between such treatment and cancer progression.

A multi-year study of rivaroxaban in patients with non-valvular atrial fibrillation demonstrated that the drug is about as safe in real-world usage as it was in phase 3 trials.

New research may help explain the connection between exocrine pancreatic insufficiency, gastric bypass surgery, and oxalate nephropathy in humans.

Researchers announced a phase 3 trial assessing secukinumab for the treatment of psoriatic arthritis met its primary endpoint (ACR 20 at week 24), possibly putting the drug on the fast track to approval.

Recent studies of anaphylaxis and other allergic reactions induced by medications have informed a new set of guidelines for the diagnosis and treatment drug hypersensitivity.

A research review concludes that older men who receive testosterone replacement via injection may enjoy greater benefits and face fewer risks than those who use transdermal or oral testosterone formulations.

Men with low testosterone treated with injections faced higher risk of myocardial infarction, unstable angina, and stroke compared to men treated with gel-based testosterone replacement therapy.

A number of widely reported studies have concluded that the rapid growth in testosterone therapy prescriptions has led to overuse, but an analysis published in Urology indicates that underuse may also be a problem.

Data from two observational registries indicated that long-term testosterone replacement therapy in diabetic men was associated not only with better sexual function and weight loss, but also significant reductions in blood sugar.

Guidelines for the use of testosterone replacement therapy call for initial and ongoing tests of patient testosterone levels, but new research found a significant problem with such recommendations.

New research finds that flushing and dyspnea may help physicians spot unusually severe cases of anaphylaxis, cases that will put patients at particular risk and require more than a single dose of epinephrine.

A new meta-study of bee venom therapy finds considerable risk of anaphylaxis and other reactions, concluding that only experts should offer it to patients.

Study results presented at the 2015 Congress of the European League Against Rheumatism show treatment with apremilast can improve common, painful manifestations of psoriatic arthritis.

A small study of children with cystic fibrosis found ghrelin and leptin levels correlate with nutritional status and can be an early marker of exocrine pancreatic insufficiency.

Researchers have shown that the tendency of atrial fibrillation to impair cognitive function stems, at least in part, from a reduction in blood flow to the brain.

New research finds that low testosterone levels are strongly associated with low bone density (BMD) - even in relatively young men.

A new analysis has found that low levels of vitamin D are independently associated with low levels of testosterone in healthy middle-aged men.