Treating 5 Percent of All Patients with Hepatitis C Would Reduce Costs and Total Infections
October 8th 2015Comparing current treatment models to lessons learned in the early days of the AIDs epidemic, University of Southern California researchers are advocating that more than just the sickest patients with hepatitis C be treated with new drugs that have much higher cure rates than past regimens.
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Study Shows Increase in Hepatitis C Rate Among Some HIV-Positive Men
September 18th 2015Researchers conducted an analysis of studies that spanned more than two decades and found that outbreaks of sexually transmitted hepatitis C is increasing among men who are HIV positive and have sex with other men.
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Hepatitis C Virus Enzyme Could Provide Novel Drug Target
September 18th 2015Scientists in Italy say they have gained new insight into how the hepatitis C virus replicates as a result of studying the behavior of a key enzyme and creating a computer model that shows how it interacts with the viral genome.
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Drug Cocktail Boasts 97% Hepatitis C Cure Rate in Patients Coinfected with HIV
July 22nd 2015A novel hepatitis C treatment that combines sofosbuvir with another drug not yet approved in the US had a 97% success rate in a group of patients who were coinfected with HIV, according to researchers from the University of California, San Diego School of Medicine.
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Combination Treatment Cures Hepatitis C in Patients with Compensated Liver Cirrhosis
June 29th 2015Recent study showered 100 percent sustained virologic response at 12 weeks in patients with hepatitis C genotype 1b who received treatment with an interferon- and ribavirin-free combination drug.
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England's NHS Allots Big Bucks for Hepatitis C Treatment
June 12th 2015England's National Health Services has increased its budget for new hepatitis C drugs to a whopping £190 million, amounting to nearly 215 million US dollars (at current exchange rates) and more than triple the amount allotted last year.
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Researchers Test New Model for Predicting Hepatitis C Risk
May 28th 2015Researchers from the University of Michigan say a new model that uses routine laboratory tests and machine-learning methods to better predict hepatitis C progression can be used to guide patients and doctors through important treatment decisions.
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5 New Hepatitis C Drugs Added to WHO "Essentials" List
May 13th 2015The essential medicines list put out by the World Health Organization (WHO) now includes five new hepatitis C drugs that show great promise in curing the disease in millions of people. However, the WHO also warned financial stumbling blocks could greatly hinder efforts to make treatment equitable throughout the world.
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Hepatitis C and Injection Drug Use Top Targets of CDC Prevention Efforts
May 13th 2015In a continuing effort to curb the spread of hepatitis C among the riskiest populations, government health officials recently held a webinar to discuss links between opioid injection drug use and increased cases of the liver disease.
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Hepatitis C Behind Bars May Be Too Costly to Cure
April 16th 2015A study of Rhode Island state prisons shines a spotlight on the trouble correctional facilities face because they aren't financially equipped to bear the budget-busting costs of new drugs to treat all inmates chronically infected with hepatitis C.
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FDA Warns of Serious Slowing of Heart Rate with Hepatitis C Drugs and Amiodarone
March 28th 2015The FDA approved label warning changes for two Gilead Sciences hepatitis C drugs after one person died and nine others had serious reactions when the drugs were coadministered with amiodarone, a drug used to treat irregular heartbeat.
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Cost Burden of New Hepatitis C Drugs, Effect on Health Care System, Analyzed
March 22nd 2015Researchers who analyzed the cost of new high-price hepatitis C drugs found them to be cost effective for most patients yet likely to weigh down budgets of US government and insurance providers for years to come like no drug ever before.
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Using Viral Load to Predict Hepatitis C Cure Differs with New Drugs, Studies Suggest
March 15th 2015Detectable hepatitis C viral loads seen when treatment has ended in patients taking direct acting antiviral therapy is not necessarily an indication that the drug regimen didn't work, according to results from a recent study.
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Kidney Disease Risk Higher with Longer Exposure to Antiretrovirals, Study Finds
March 1st 2015Chronic kidney disease developed in association with exposure to antiretrovirals in people with initially normal levels of estimated glomerular filtration rate (eGFR) was not limited to increased incidence immediately after starting therapy but in fact increased over time and exposure.
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New Formulation Compares Favorably to Current, Commonly Used Tenofovir Dose
March 1st 2015Tenofovir alafenamide, which results in 90% lower circulating plasma tenofovir than standard tenofovir disoproxil fumarate, is associated with similar virologic response rates as the standard regimen, but with an improved safety profile.
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Combo Drug Shows High Hepatitis C Cure Rates in Patients Coinfected with HIV
March 1st 2015An interferon/ribavirin-free pill that combines two drugs to treat patients with certain genotypes of hepatitis C who are also infected with HIV was found to be highly effective in a 12-week trial, clearing the hepatitis C virus from almost all the patients involved.
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