Finding love despite illness: Examining emerging disease-focused dating Websites
May 7th 2010Dating can be a terrifying and frustrating endeavor, especially if you are shy or socially awkward. It may seem impossible to even meet someone when you find yourself struggling to muster up the courage to initiate a conversation.
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Evernote for Oncologist: Connecting the paper and digital realms
April 30th 2010Cloud computing, or the storage of data on the Internet, is taking off at a rapid pace, with numerous start-ups and established entities vying for consumer attention and amassing considerable user bases very quickly.
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The Invisible Killer in Your Home: Understanding Radon, Testing, and Mitigation
January 19th 2010Radon is an invisible, odorless, and tasteless radioactive gas that is released into the air or dissolves into groundwater as uranium in rocks or soil decays. It was classified as a human carcinogen in 1988 by the International Agency for Research on Cancer, but the ill health effects of this invisible killer had been observed for centuries in Europe.
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Targeted Agent Appears Promising in Inducing Cancer Cell Apoptosis in Chronic Leukemia Model
December 9th 2009Current treatments for chronic lymphocytic leukemia (CLL) can be damaging to the immune system, leaving patients vulnerable to infections, which is the primary cause of death for many patients with CLL. According to a study presented at the 51st Annual American Society of Hematology Meeting, a new oral agent called 17-DMAG may avoid this problem. Mouse models assessing 17-DMAG showed this agent to be highly selective for CLL cells, while having minimal effect on normal immune cells, suggesting the agent leaves the immune system intact.
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New Orleans, LA - Although studies have shown plerixafor (Mozobil) plus granulocyte-colony stimulating factor (G-CSF) mobilizes more CD34+ cells than G-CSF alone prior to autologous hematopoietic stem cell transplant, many patients receive chemotherapy followed by G-CSF to mobilize CD34+ cells before transplantation. In a poster session presented at the 51st ASH Annual Meeting, Paul J. Shaughnessy, MD, medical director, Adult Blood and Marrow Transplant, Texas Transplant Institute, San Antonio, Texas, reported the results of a retrospective study that found plerixafor plus G-CSF mobilization resulted in more predictable days of collection, no weekend apheresis procedures, and no unscheduled hospital admissions compared with chemotherapy plus G-CSF.
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PROPEL Study Reinforces Viability of Pralatrexate in Peripheral T-cell Lymphoma; Cost Questioned
December 8th 2009During the 51st ASH Annual Meeting, several new data from the PROPEL trial were released, including updates on the ORR and safety of pralatrexate in patients with PTCL and data on the correlation between baseline methylmalonic acid status and mucositis severity in this population. While the data reinforce pralatrexate as a viable treatment in patients with relapsed or refractory PTCL, some question whether the drug confers enough of a benefit to warrant its $30,000 per month cost.
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