Connor Iapoce

At 12 months of the CAPLA trial, the addition of posterior wall isolation to pulmonary vein isolation led to no significant improvements in freedom from atrial arrhythmia.

A secondary analysis of a cluster RCT indicated the Texas Sprouts intervention led to improvements in glucose control and reduced LDL-C in high-risk schoolchildren.

The medication was approved for the as-needed treatment or prevention of bronchoconstriction and to reduce the risk of exacerbations in people with asthma aged 18 years and older.

Results from the REGARDS study suggest traditional CKD risk factors were associated with higher risk of incident CKD and eGFR decline in Black individuals, compared to White individuals.

Eight studies provided evidence to suggest the relationship between diabetes and the onset of frozen shoulder, but more high-quality cohort studies may be necessary to better understand the nature of the relationship.

Five years of treatment follow-up in the Fight Retinal Blindness registry provided evidence that SRF protected against the development of subfoveal and extrafoveal macular atrophy.

MAFLD-lean and MAFLD-diabetes subgroups recorded a higher risk of all-cause and disease-specific mortality compared to the MAFLD-overweight/obese group.

Both rates of macular vessel density loss and ganglion cell complex thinning are associated with central visual field loss in eyes with early glaucoma.

The COACH trial reported a hospital-based strategy led to lower risk of death from any cause or hospitalization for cardiovascular causes within 30 days than usual care in patients with acute heart failure.

Patients with AF experienced worse 90-day outcomes than those without AF, even with comparable, successful reperfusion outcomes.

The phase 3 GOBI study endpoints was significantly greater with NOV03 versus hypotonic saline on the change from baseline at Week 8.

The retrospective study reported the presence of ADAs was associated with lower drug levels, and higher ADA levels were associated with increased risk of TNFi therapy failure.

The lowest mean utility value was observed in the most severe disease state of constant diplopia and large proptosis.

A post-hoc analysis suggests that increased dietary nitrate intake was associated with a decreased risk of late AMD, but this association was attenuated after the addition of plant-based dietary patterns.

The data from the DPPOS cohort report no difference in AMD presence or severity between metformin, intensive lifestyle intervention, and placebo arms.

Complete healing occurred after 4 weeks in 6 of the 10 RGN-259-treated subjects and in 1 of the 8 placebo-treated subjects.

To celebrate the end of 2022 and the advances witnessed in the past year, our editorial team has created a list of the top 8 most popular pieces of content related to endocrinology from 2022.

Study data show the five-year incidence of fibrosis, atrophy, and MH were 34%, 26%, and 8%, respectively.

Cross-sectional data showed that rEZR reduced with increasing age, while longitudinal data indicate rEZR declined at a rate of ‒2.1 AU per year.

A look at the defining moments of the past year and what is expected to come in 2023.

As physician demands continue to climb in the high-demand specialty, patient-reported outcomes have emerged as a viable tool in assessment and care.

A new Q&A focuses on hybrid telehealth in ophthalmology and subspecialty-level care, and its potential to create new opportunities and increase access for patients.

A continued discussion with Dr. Bays on anti-obesity therapies down the line and where they might be in the near future.

Anti-obesity medications have the potential for significant weight reduction, but the development of newer agents may lead to an even greater change in obesity care.

A moderate negative correlation was observed between changes in BCVA and changes in CST at weeks 12 and 24.

Dupilumab use surpassed all conventional systemic drug use since its introduction in 2017 until the end of the study in 2020-21.

The ERF and ERF-free groups had similar best visual acuity gains from baseline to week 52.

Patients with DR who received intravitreal anti-VEGF injections had a risk of cardiovascular events similar to those who received laser or steroid treatment

An analysis of the change from preoperative to final BCVA showed no difference between the deferred and immediate surgery subgroups.

SB11 and ranibizumab appeared to have comparable immunogenicity and safety profiles in a post-hoc analysis of a phase 3 equivalence trial.