Hand Washing Lowers Risk of Allergy in Children
August 5th 2015Using a questionnaire based survey of children from Scandinavia, these authors correlated asthma, eczema, and rhino-conjunctivitis, and found lower rates of these outcomes in those who hand washed as opposed to those who machine washed their dishes.
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Exercise is Good and Media Coverage of Exercise is Bad
July 13th 2015The reaction to an editorial claiming that exercise alone will not help patients lose weight is illustrative of the biases held by certain groups and underscores the need for greater education and awareness of the science of weight loss for patients and clinicians.
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Diabetes Risk is Reduced by Egg Consumption
July 13th 2015A recent study out of Finland found that men who ate chicken eggs on a regular basis had a lower risk of developing type 2 diabetes mellitus. Like a number of other recent studies this article stands in contrast to what was once the conventional wisdom: that eating foods high in cholesterol would increase your risk of heart disease and its risk factors.
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Proton Pump Inhibitors Increase CHD Risk
July 1st 2015There is consistent observational data that identifies concomitant use of proton pump inhibitors for gastroesophageal reflux disease and clopidogrel following acute coronary syndrome increases the risk of recurrent cardiovascular events. While a variety of theories exist (lower pH alters absorption, etc.), no clear factor has been identified.
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Taking Another Look at the Link Between Vaccination and Autism
July 1st 2015This Meta analysis verified that there is no relationship between MMR vaccinations and the development of autism, and found no evidence of publication bias, implying that the medical literature was not altered to hide an association.
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Rapid Testing for Strep Pharyngitis alone; Culture Not Needed
June 9th 2015This was a systematic review and meta-analysis examining the accuracy of rapid antigen diagnostic tests (RADTs) for group A strep (GAS) pharyngitis in children and adults as well as differences between studies already performed.
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Can Tamoxifen Prevent Breast Cancer?
June 9th 2015The IBIS-I randomized control trial included women of ages 35-70 from 37 health centers in eight countries from April, 1992, until March, 2001 that were deemed to be at increased risk of developing breast cancer (by virtue of family history of breast cancer or abnormal benign breast disease), and randomized to treatment with oral tamoxifen or placebo for 5 years.
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How Cataract Surgery Affects Costs and Outcomes for Patients
June 9th 2015This is an observational cohort study of Medicare beneficiaries of patients undergoing cataract surgery in the year 2011. Using multivariate analysis, the authors determined the relationship between preoperative testing and patient characteristics, health systems' characteristics, surgical setting, surgical care team, and the occurrence of a preoperative office visit.
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The Parable of the Salt and the Evolving Medical Consensus
May 21st 2015Changes in the way we think about sodium intake and cardiovascular risk, calcium supplementation, and other topics should remind us all of the advice we heard on the first day of medical school: 50% of what you learn here is wrong or going to disappear over your career; we just don't know which 50%.
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Improving Child Health by Screening for Social Determinants
May 11th 2015This cluster randomized controlled trial evaluated whether a screening and referral system for social determinants of health (called WE CARE) at well child visits resulted in receipt of more community resources for families.
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Eat Fiber: One Simple Message for Weight Loss
May 11th 2015This study was a randomized, controlled trial of 240 adults with metabolic syndrome who were assigned to follow either the single-component dietary recommendation of increased fiber consumption (≥30g/d), or the multi-component American Heart Association (AHA) dietary guidelines. The primary outcome measure was weight loss at 12 months.
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Does Sodium Restriction Improve Cardiovascular Outcomes?
April 8th 2015Dietary sodium restriction is frequently recommended as a means to manage hypertension, congestive heart failure and cardiovascular disease. However, with the growing focus on patient-centered outcomes rather than disease-centered outcomes, the importance of sodium restriction becomes less clear.
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Do Statins Alter or Impair Cognitive Ability; A Systematic Review and Meta Analysis
March 11th 2015In 2012 the FDA issued a warning about the potential for statins to induce adverse effects on cognition; this systematic review and meta analysis of randomized controlled trials was completed to determine if this was true.
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Looking at the Connection Between Pertussis Vaccinations and Asthma
March 11th 2015Based upon casual observation, some have suggested that the rise in the diagnosis and incidence of asthma is related to the pertussis vaccine. This study in Sweden attempted to determine if such a relationship exists.
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A Simple Solution to Embolism in Atrial Fibrillation
February 2nd 2015For patients with non-valvular atrial fibrillation, preventing stroke using anti-coagulation medication is the standard of care. This study looked at using a device that closes off the left atrial appendage of the heart to determine if it too would lower the risk of stroke.
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