Normalizing Blood Pressure May Prevent a Second Stroke
April 7th 2014Although many clinicians presumed patients with poor collateral blood vessel formation near their stroke site should have their blood pressure left high to prevent a second stroke, a study published in Neurology found lowering blood pressure to normal levels reduces subsequent stroke risk more effectively.
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Clue Emerges About Rare Disease Associated with MS Drug
March 31st 2014Researchers at the National Institute of Neurological Disorders and Stroke may have found why patients taking the multiple sclerosis medication natalizumab (Tysabri) have a high risk of developing a rare brain infection that can be fatal.
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Congressional Bills Seek Ban on FDA-Approved Zohydro
March 25th 2014Legislation in both the US House of Representatives and the Senate seeks to reverse the FDA's recent approval of Zogenix's hydrocodone-only painkiller Zohydro, because the drug's formulation does not include an abuse deterrent.
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New PCI Guidance Aims to Increase Safety, Maintain Quality
March 25th 2014A new guidance document on percutaneous coronary intervention (PCI) cites the need for new safety and quality protocols to address the increasing number of PCIs performed at centers with no on-site cardiac surgery backup available.
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Childhood Immunizations Save Thousands of Lives, Billions of Dollars
March 18th 2014A new economic analysis finds that the US childhood immunization schedule will prevent 42,000 early deaths and 20 million cases of disease, saving $13.5 billion in direct costs over the lifetime of a single cohort.
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Healthcare Coalition Decries FDA Approval of Extended-Release Zohydro
March 3rd 2014A 40-member coalition partly comprised of physician experts on opioid addiction treatment and overdose prevention is asking the US Food and Drug Administration to rescind its approval of extended-release Zohydro (hydrocodone bitratrate), given the drug's perceived dangers to the public.
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Alzheimer's Agitation Eased by Citalopram, But With Severe Adverse Effects
February 26th 2014In a recent clinical trial, Celexa (citalopram) reduced agitation in patients with probable Alzheimer's disease (AD) compared to placebo, but the drug also produced severe cognitive and cardiac adverse events that prescribers must consider.
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Ear Drops Beat Oral Medications in Children With Tympanostomy-Tube Otorrhea
February 21st 2014A new study suggests antibiotic-glucocorticoid ear drops are superior to oral medications in children who suffer from acute otorrhea following the insertion of tympanostomy tubes for recurrent ear infections.
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FDA Panel Votes Against Naproxen's Cardiovascular Safety Claim
February 19th 2014A US Food and Drug Administration (FDA) advisory panel has not found enough clinical evidence to conclude that naproxen presents a lower risk of cardiovascular (CV) thrombotic events than other nonsteroidal anti-inflammatory drugs (NSAIDs).
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Late-Onset Alzheimer's Disease in Both Parents May Boost Dementia Risk in Adult Offspring
February 18th 2014Patients who are free of dementia but have 2 parents with late-onset Alzheimer's disease may show signs of the disease in brain scans several years, if not decades, before they display clinical symptoms.
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