Genotyping Promises Precision Treatment of Atopic Eczema
December 19th 2016The first study to associate genetic variances linked to skin barrier deficiencies and immune response in atopic eczema/dermatitis with the responses to treatment over several years has moved the field closer to individualizing precision therapies for the condition.
Read More
Probiotics May Prevent Atopic Dermatitis if Microbiome Cooperates
December 13th 2016Previous research showed probiotics given to pregnant women during certain stages of pregnancy and post delivery reduced the likelihood of atopic dermatitis in their children. Recently published reports; however, may not agree.
Read More
Atopic Dermatitis Patients Risk Contact Dermatitis from Topical Treatments
December 12th 2016Children with atopic dermatitis (AD) were reported to have a greater risk for developing contact dermatitis from some common ingredients of topical products than those with a history of contact dermatitis but no AD, in a recent comparison of patch testing responses in both groups.
Read More
Corticosteroid Success Linked to Differences in Bronchial Microbiome
December 7th 2016Individuals with atopic asthma were recently found to have a distinctive bronchial bacterial microbiome that not only differs from those without asthma, but between asthmatics with phenotypes more responsive or resistant to inhaled corticosteroids.
Read More
Dermatologists Name Favorite Drugs in Pediatric Atopic Dermatitis
November 23rd 2016In a recent survey of pediatric dermatologists, cyclosporine (Neoral/ Novartis, SandIMMUNE/ Sandoz, others) was the most common choice of systemic agent to treat severe pediatric atopic dermatitis (AD), followed by methotrexate (Trexall, Teva, others).
Read More
Discontinuing Omalizumab Can Exacerbate Asthma
November 22nd 2016Patients who discontinued long-term treatment with omalizumab (Xolair/Genentech and Novartis) were more likely to experience an episode of severe asthma exacerbation during a one-year monitoring period than those who continued the treatment, in a recent study to determine whether therapeutic effect persists after discontinuation.
Read More
Which Emollient Makes Atopic Dermatitis Worse?
November 21st 2016Multiple measurements of skin integrity and function were applied to distinguish between the effects of topical emollient products in a recent study. Two popular products in the UK were determined to transiently improve the skin barrier that is thought to be defective in atopic dermatitis (AD), and another product was confirmed to be damaging.
Read More
How Did Researchers Miss Asthma Drug's Potential?
November 10th 2016One year after the November 2015 FDA approval of mepolizumab (Nucala, GlaxoSmithKline) to treat severe asthma with eosinophilic phenotype, a review considers how initial studies missed its effectiveness, the subsequent evidence that supported its utility, and possible future applications.
Read More
Testing Ustekinumab for Severe Atopic Dermatitis
October 31st 2016Approved by the FDA to treat plaque psoriasis, psoriatic arthritis, and active Crohn's disease, ustekinumab appeared to benefit patients with severe atopic dermatitis (AD) in a small study seeking to correlate its immunologic effects with clinical efficacy.
Read More
Too Many Ways to Measure an Itch, Derm Study Finds
October 12th 2016Dermatitis researchers use far too many instruments in measuring symptoms of skin ailments, a study found. Symptoms of atopic ezcema/dermatitis (AD) were found in a systematic review of randomized controlled trials (RCTs) to be most often characterized from composite measures rather than stand-alone symptom severity rating instruments, and thirty different instruments were found to have been used across 378 trials.
Read More
Early Subcutaneous Allergen Immunotherapy Works for Certain Patients
October 12th 2016Severe atopic dermatitis (AD) symptoms of shorter duration were more likely to improve in allergen sensitized patients receiving desensitizing immunotherapy, than severe symptoms of longer duration or more moderate symptoms, according to a new observational cohort study.
Read More
Atopic Dermatitis: Immunotherapy Can Be Effective
October 10th 2016Severe atopic dermatitis (AD) symptoms of shorter duration were more likely to improve in allergen sensitized patients receiving desensitizing immunotherapy, than severe symptoms of longer duration or more moderate symptoms, according to a new observational cohort study.
Read More
Which Patients with Atopic Dermatitis Are Least Likely to Outgrow It?
October 6th 2016Childhood atopic dermatitis (AD) usually resolves before adulthood, a meta-analysis of cases showed. Those patients who did see their AD persist were more likely to be female, to have been older at onset, and to have relatively severe AD.
Read More