Patrick Campbell is the managing editor of HCPLive. Formerly the editorial lead of Endocrinology Network, Practical Cardiology, and Rheumatology Network, Patrick has spent years spearheading coverage surrounding cardiometabolic health and rheumatic disease for MJH Life Sciences. He now helps to lead coverage in each of these respective areas for HCPLive. Before joining MJH Life Sciences in 2019, he spent time as a beat reporter with the Pocono Record in Stroudsburg, PA, and Star News Group in Manasquan, NJ. He also touts experience in multimedia, having spent time as a multimedia specialist with NJ Advance Media and multimedia coordinator at the Pocono Record. Follow him on Twitter @RealPatCampbell or reach him via email at PCampbell@mjhlifesciences.com.
COVID-19-Related Stress Could Trigger Increased Insulin Resistance, Transient Diabetes
March 1st 2022A retrospective review with nearly a year of follow-up indicates nearly 40% of newly diagnosed diabetes at COVID-19 admission regressed to prediabetes or normoglycemia at follow-up, suggesting stress hyperglycemia induced by COVID-19-related acute stress could be driving rates of diagnosis.
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FDA Issues CRL for Bardoxolone Methyl in CKD Caused By Alport Syndrome
February 28th 2022The CRL for bardoxolone methyl for treatment of CKD caused by Alport syndrome comes less than 3 months after an FDA advisory committee voted unanimously against approval of Reata Pharmaceutical's once-daily, orally administered activator of Nrf2.
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Bardoxolone Rejected by FDA for CKD Caused by Alport Syndrome
February 26th 2022Announced by Reata Pharmaceuticals on February 25, the Complete Response Letter from the FDA for bardoxolone methyl comes a little over 2 months after an FDA advisory committee voted unanimously against approval of the once-daily, orally administered activator of Nrf2.
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Artificial Intelligence Tool Can Identify Left Ventricular Hypertrophy, Determine Cause
February 25th 2022A new study indicates a novel, 2-step deep learning algorithm developed using echocardiogram videos was able to identify left ventricular hypertrophy and the cause with greater accuracy than trained clinicians.
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FDA Approves Empagliflozin for Treatment in Adults with Heart Failure
February 24th 2022Announced on Feb. 24, the approval indicates the SGLT2 inhibitor for reducing risk of CV death and hospitalizations for heart failure in adults with heart failure and is supported by data from the EMPEROR-Preserved trial.
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Primary Care Interventions Help Drive Increased Physical Activity in Adult Patients
February 24th 2022An analysis of data from more than 16,000 patients demonstrates the added benefit interventions delivered in primary care settings can have on physical activity levels among adult patients.
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Ross Procedure Safe, Effective For Adults Undergoing Aortic Valve Surgery
February 23rd 2022An analysis comparing 15-year outcomes following Ross procedure and biological or mechanical aortic valve replacement provides insight into the risk of mortality and other adverse outcomes associated with each procedure.
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Study Details Causal Effect of Obesity on Diabetic Nephropathy
February 22nd 2022Data from an analysis of more than 150,000 patients suggests increased BMI was associated with more than a 3-fold increase in odds of diabetic nephropathy in patients with type 2 diabetes, but this effect was more apparent in women who experienced a 14-fold increase in odds of diabetic nephropathy.
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Assisted Reproductive Technologies Could Increase Risk of Arrhythmia, Kidney Injury
February 22nd 2022An analysis of data from the National Inpatient Sample suggests pregnancies conceived by assisted reproductive technology carried a 1.7- and 2.5-fold increase in risk for arrhythmia and acute kidney injury compared to those conceived without ART.
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FDA Expands Indication for CardioMEMS HF System, Includes NYHA Class II, Worsening HF Patients
February 21st 2022Announced by Abbott on Feb. 21, the expanded indication for the CardioMEMS HF System now includes patients with NYHA Class II heart failure and those with worsening heart failure, which expands the potential patient population by 1.2 million additional patients.
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Tandem Diabetes Receives FDA Clearance for t:connect mobile app
February 21st 2022Announced on Feb. 18, the t:connect mobile app, which pairs with the t:slim X2 insulin pump, is the first-ever FDA-cleared smartphone application capable of initiating insulin delivery on both iOS and Android operating systems, according to Tandem Diabetes Care.
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Newer Anticoagulants Have Lower Diabetic Complications Risk than Warfarin in AFib
February 18th 2022A retrospective cohort study suggests users of DOACs were at a 16% lower risk of developing macrovascular complications, a 21% lower risk of microvascular complications, and a 22% lower risk of mortality compared with warfarin users among a population of patients with diabetes and atrial fibrillation.
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Comparing Cost-Effectiveness of Management Approaches for Severe Obesity in T2D
February 16th 2022An economic evaluation using a microsimulation model comparing Roux-en-Y gastric bypass, sleeve gastrectomy, and medical therapy for severe obesity in patients with type 2 diabetes suggests gastric bypass was the most cost-effective approach.
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DOACs Associated with Fewer Diabetic Complications than Warfarin in Atrial Fibrillation
February 15th 2022Data from a national research database in Taiwan provides insight into the apparent reductions in risk associated with DOAC use compared to warfarin in patients with atrial fibrillation and diabetes.
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Stroke Risk Among Older Patients with COVID-19 Most Apparent in First 3 Days of Diagnosis
February 12th 2022Data from Medicare beneficiaries provide insight into the risk of stroke associated with a diagnosis of COVID-19 among older adults, which results suggest peaks within the first 3 days of diagnosis.
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Thrombectomy Linked to Improved Outcomes in Pediatric Large Vessel Occlusion
February 11th 2022A retrospective analysis of 10 years of stroke admissions suggests pediatric stroke patients with LVO who did not undergo thrombectomy were at 6 times greater risk of moderate to severe disability or death than those who underwent thrombectomy.
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US FDA Approves Eversense E3 CGM System, Allows Use for Up to 6 Months
February 11th 2022Announced on February 11, the approval for Eversense E3 continuous glucose monitoring system allows access to a CGM system with 6 months of longevity and is expected to be available beginning in the second quarter of 2022.
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DOACs Could Lower Bleeding, Hemorrhage Risk vs. Warfarin in Patients with CVT
February 10th 2022An international, retrospective analysis presented at ISC 2022 provides evidence suggesting use of DOACs as a treatment for cerebral venous thrombosis was associated with similar risk of recurrent clots and death as warfarin, but a 65% lower risk of major bleeding.
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Study Suggests Risk of In-Hospital Mortality from Stroke 42% Greater During Pandemic
February 10th 2022A meta-analysis presented at ISC 2022 suggests the risk of in-hospital mortality for stroke-related admissions was 42% greater among patients hospitalized during the pandemic compared to prepandemic.
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Poor Sleep Health Linked to Significant Increase in Risk of Cardiovascular Disease
February 9th 2022Using a pair of composite scores for measuring sleep health, new research from USF demonstrates the impact poor sleep health can have on risk of cardiovascular disease among adults in midlife.
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Tirzepatide Shows Utility as Add-On Therapy to Titrated Insulin in Type 2 Diabetes
February 8th 2022Data from the SURPASS-5 trial demonstrate the safety and efficacy of multiple tirzepatide doses as an add-on therapy to titrated insulin glargine for glycemic control and weight loss in patients with type 2 diabetes.
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Gestational Diabetes Increases Long-Term Risk for Wide Array of Cardiovascular Conditions
February 7th 2022Analysis of the UK Biobank cohort suggests presence of gestational diabetes was associated with a 33% increase in risk of CAD, 67% increase in risk of myocardial infarction, 69% increase in risk of stroke, and 42% increase in risk heart failure.
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