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Alogliptin: The newest agent to fight the diabetes pandemicAccording to the American Diabetes Association (ADA), 23.6 million children and adults have diabetes (8% of the US population) and another 5.7 million cases remain undiagnosed. Epidemiologists predict that these statistics will double by 2030, further taxing the healthcare system. Medical expenditures are approximately 2.3 times higher for diabetic versus nondiabetic patients, and the annual cost of diabetes is estimated to be $116 billion.
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Child VaccinationsAs measles make a nationwide comeback, are parents who refuse to vaccinate their children contributing to the problem?
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Contemporary stenting practices, optimal antiplatelet and antithrombotic therapy, and the continuum of care of patients with cardiovascular disease: A roundtable discussionThe first stent was invented in 1969 by Charles Theodore Dotter, experimenting on canine peripheral arteries.
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E-patients: The Genie is Out of the BottleMelissa received a metastatic lung cancer diagnosis just a few weeks after celebrating her 40th birthday. Within hours of hearing her diagnosis from her primary care physician, she started searching the Internet about her disease and what to expect in terms of treatments.
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Noninvasive coronary angiography with multislice computed tomography and myocardial perfusion imagingA total of 114 patients with an intermediate pretest likelihood of coronary artery disease were evaluated with both multislice computed tomography (MSCT) and myocardial perfusion imaging (MPI). Results showed that in the majority of cases, a normal MSCT scan was associated with normal perfusion. However, only half of patients with significant stenoses showed abnormal perfusion. Accordingly, MPI and MSCT are intrinsically different techniques and appear to be complementary rather than overlapping as they provide information on atherosclerosis versus ischemia, respectively.
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Massachusetts Healthcare Reform and Possible Insights into Affordable Care Act FutureImplementation of Massachusetts health care reform reduced all-cause mortality and mortality from causes amenable to health care
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Assessing risk through "inspired" careThis retrospective subanalysis of the Adenosine Sestamibi SPECT Post-Infarction Evaluation (INSPIRE) trial shows that early adenosine sestamibi stress testing is not only safe early after myocardial infarction (MI), but can also be very useful to identify patients at very low risk for events in the first year after discharge.
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Insights on Rare MICPCH Syndrome Could Help with Autism, EpilepsyResearch into a rare neurological disorder may help researchers working on more common diseases including autism and epilepsy.
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Alcohol consumption and cardiovascular riskWe generally assume that having a good time must be bad for you,and no one would deny that irresponsible alcohol consumption takes a tremendous economic, social, and health-related toll on diverse populations all around the globe.
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Drug-eluting stents and diseased saphenous vein grafts: Long-term risk in RRISCProgressive disease in saphenous vein grafts remains a major short-term and long-term clinical challenge after surgical revascularization.
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Safety and Efficacy of Drug-Eluting Stents in WomenThe safety and efficacy of drug-eluting stents are proven in the general population, but how do they perform in women?
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Late mortality with sirolimus-eluting stents in diseased saphenous vein graftsIn a secondary post-hoc analysis of the Reduction of Restenosis in Saphenous Vein Grafts with Cypher (RRISC) trial, we compared the long-term safety of sirolimus-eluting stents (SES) with bare-metal stents (BMS) in diseased saphenous vein grafts
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What Physicians Need to Know About Obesity Medication and Side EffectsWith the global epidemic of obesity showing no signs of waning, physicians should be aware of the cardiac side effects of weight-loss drugs.
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How the Older Americans Act Facilitates Aging in PlaceMore than 90% of adults over 65 prefer to stay in their current residence.
