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FDA Approves Acoramidis (Attruby) for ATTR-CMWith approval, acoramaidis becomes the first agent with a label specifying near-complete stabilization of TTR.
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Wall Street Journal Op-Ed: Trying to Save Lives in Port-Au-PrinceA lot of amputees and the paralyzed will need lifelong care.
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Late events, less use of drug-eluting stents?The study by Handke et al focuses on one of the most controversial areas of interventional cardiology—the clinical downside of treatment with drug-eluting stents (DES).
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Is circulating heat shock protein 60 a marker for susceptibility to cardiovascular disease in patients with diabetes?The vital cell stress protein, heat shock protein (Hsp)60, has recently been found in the circulation of healthy subjects over an extremely large concentration range. We performed an analysis of subjects with diabetes to determine whether Hsp60 is associated with biochemical markers of cardiovascular disease. Results showed that high circulating levels of Hsp60 are associated with clinically manifest cardiovascular disease. Hsp60 has cytokine-like actions, which may be responsible for this association.
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Metoprolol for the prevention of vasovagal syncopeIn the Prevention of Syncope Trial, we evaluated whether beta-blocker treatment with metoprolol was beneficial for the treatment of patients with vasovagal syncope. Results showed little evidence that metoprolol was effective in reducing the burden of syncopal symptoms. In a substudy analysis, neither age nor response to isoproterenol was useful in selecting which patients might benefit from metoprolol.
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Everyone Loves e-Prescribing! Right?Electronic prescribing is rapidly gaining support from a diverse array of healthcare organizations, government agencies, and technology corporations.
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The Core of Compassion in Physician-Assisted SuicideThe practice has only reached a handful of states in 25 years of proposal. What drives the arguments for and against it?
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Large-scale clinical epidemiology of stable angina in women and menWe performed a whole-country study using linked health care records in Finland and showed that stable angina as the initial symptomatic manifestation of coronary disease occurs as frequently in women as it does in men. Among easily recognized subgroups, the absolute rates of prognostic outcomes were similarly high in women and men.
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Barriers Remain for Better Hepatitis C Virus CareTreatment initiation was lower among Medicaid and private health insurance recipients aged 18-29 years, compared with patients aged 50-59 years.
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The Relative Unimportance of Diagnosis in PsychiatryShrinkRap guest blogger Dr. Mitchell Newmark looks at the pitfalls of diagnosis in psychiatry.
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Nurses Are the Center of COVID-19 Crisis Communication. Is Tech Helping?A deeper look at how nurses are affected during the current health pandemic.
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Transcatheter occlusion of the left atrial appendage to prevent stroke in atrial fibrillationWe conducted 2 feasibility studies to assess the performance and safety of the percutaneous left atrial appendage (LAA) transcatheter occlusion system for the prevention of stroke in high-risk patients with nonrheumatic atrial fibrillation. Results showed that percutaneous LAA occlusion can be performed using the device at acceptable risk. This procedure may be particularly useful for patients at increased risk of ischemic stroke with a contraindication to anticoagulation therapy.
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Advances in the Treatment of Diabetic Kidney DiseaseOn this episode of MEDcast, Diana Isaacs, PharmD, BCPS, BC-ADM, CDCES, and Natalie Bellini, DNP, FNP-BC are joined by Dr George Bakris to discuss the latest advances in treatments and comprehensive care for patients with diabetes and chronic kidney disease.
