Authors
Latest:
Value of the 6-minute walk test in older patients with chronic heart failureWe assessed the prognostic value of the 6-minute walk test (6-MWT) among 1592 subjects with differing degrees of left ventricular systolic dysfunction (LVSD). We found that the 6-MWT was an independent predictor of mortality, particularly among patients with more than mild LVSD. The 6-MWT provides less prognostic utility in patients with mild or lesser LVSD, however.
Latest:
Hyperpigmented Back Lesion in a Young WomanThis 28-year-old woman presented with a large hyperpigmented patch on the right side of her upper back. Although the lesion developed over the past 2 years, it has been "sinking in" over the past 2 weeks. The patient denies any trauma, pain, discomfort, or pruritis, as well as any family history of cancers, lymphoma, or autoimmune disease. However, she has a history of gastroesophageal reflux disease and onychomycosis, and her grandfather has a similar lesion.
Latest:
Contemporary cardiac imaging in hypertrophic obstructive cardiomyopathyFeatures of hypertrophic obstructive cardiomyopathy (HOCM) include obstruction at the left ventricular outflow tract (caused by a markedly thickened proximal interventricular septum) and systolic anterior motion of the mitral valve. The case discussed here illustrates several classic features of this disease including clinical presentation, diagnostic workup, and noninvasive and invasive management.
Latest:
Is There a Relationship between Early Statin Compliance and a Reduction in Healthcare Utilization?Compliance with statin therapy in the first two years of use may reduce hospitalization rates and direct medical costs in the subsequent year.
Latest:
Metoprolol for the prevention of vasovagal syncopeIn the Prevention of Syncope Trial, we evaluated whether beta-blocker treatment with metoprolol was beneficial for the treatment of patients with vasovagal syncope. Results showed little evidence that metoprolol was effective in reducing the burden of syncopal symptoms. In a substudy analysis, neither age nor response to isoproterenol was useful in selecting which patients might benefit from metoprolol.
Latest:
Alogliptin: The newest agent to fight the diabetes pandemicAccording to the American Diabetes Association (ADA), 23.6 million children and adults have diabetes (8% of the US population) and another 5.7 million cases remain undiagnosed. Epidemiologists predict that these statistics will double by 2030, further taxing the healthcare system. Medical expenditures are approximately 2.3 times higher for diabetic versus nondiabetic patients, and the annual cost of diabetes is estimated to be $116 billion.
Latest:
Higher Dose of Fulvestrant Associated With Improved Survival in Advanced Breast CancerPostmenopausal women with advanced estrogen receptor–positive breast cancer lived longer when they received a 500-mg dose of fulvestrant as compared with a 250-mg dose.
Latest:
Prognostic value of multislice computed tomography coronary angiographyWe evaluated 100 subjects who underwent multislice computed tomography (MSCT) to assess the presence and severity of coronary artery disease (CAD) and to determine the occurrence of coronary events (including cardiac death, nonfatal myocardial infarction, unstable angina requiring hospitalization, and revascularization) over a follow-up period of 16 months.
Latest:
Weight-adjusted Dosing of Dalteparin Prevents VTE in Advanced Pancreatic Canceroncology,oncology nursing,ECCO/ESMO,ECCO,ESMO,dalteparin,VTE,pancreatic cancer
Latest:
TechSectors: Mobile/Wireless: iPhone 3G, the First 30 DaysLast year, I promised myself not to accept waiting in line for the iPhone "classic" and was fortunate enough to sneak into an Apple store late one night to purchase one without any hassles.
Latest:
Rivaroxaban: A potential replacement for warfarin?Millions of people in the United States require chronic anticoagulation to prevent thromboembolism secondary to chronic atrial fibrillation (AF), pulmonary hypertension, mechanical valve replacements, and other prothrombotic conditions.
Latest:
Diabetes Clinic, Part 2 - Clinically Effective Approaches to Meeting the American Diabetes Association's Guidelines: Blood Pressure Levels, Renal Evaluations, and Physical ExaminationsIn addition to promulgating standards of care regarding glycated hemoglobin (HbA1c) and low-density lipoprotein (LDL) cholesterol, which were discussed in part 1 of this series, the American Diabetes Association (ADA) has also outlined blood pressure goals. This report will review these blood pressure goals and discuss important components of the physical examination for diabetic patients, including eye and renal evaluations.
Latest:
Making History: The Epilepsy Phenome/Genome ProjectThis groundbreaking study aims to create a national resource to guide neurologists in selecting medications that are more effective and cause fewer, if any, side effects than currently available options.
